Challenges Facing Antimicrobial Stewardship Programs in the Endemic Region for Coccidioidomycosis.

Open Forum Infect Dis

Valley Fever Center for Excellence, University of Arizona, Tucson, Arizona, USA.

Published: June 2024

Coccidioidomycosis poses a significant cost and morbidity burden in the United States. Additionally, coccidioidomycosis requires constant decision-making related to prevention, diagnosis, and management. Delays in diagnosis lead to significant consequences, including unnecessary diagnostic workup and antibacterial therapy. Antifungal stewardship considerations regarding empiric, prophylactic, and targeted management of coccidioidomycosis are also complex. In this review, the problems facing antimicrobial stewardship programs (ASPs) in the endemic region for coccidioidomycosis, consequences due to delayed or missed diagnoses of coccidioidomycosis on antibacterial prescribing, and excess antifungal prescribing for prevention and treatment of coccidioidomycosis are elucidated. Finally, our recommendations and research priorities for ASPs in the endemic region for coccidioidomycosis are outlined.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11181196PMC
http://dx.doi.org/10.1093/ofid/ofae041DOI Listing

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