AI Article Synopsis

  • Acquired generalized lipodystrophy (AGL) is a rare condition marked by the loss of body fat and various metabolic issues, often starting in childhood or adolescence.
  • There are three types of AGL: type 1 involves panniculitis, type 2 is related to autoimmune diseases, and type 3 is idiopathic (unknown cause).
  • This report discusses a specific case of type 1 AGL in a healthy 3-year-old girl who showed symptoms like red subcutaneous nodules, fat loss, and findings consistent with lobular panniculitis.

Article Abstract

Acquired generalized lipodystrophy (AGL) is a rare disease characterized by variable loss of adipose tissue and concurrent metabolic derangements, typically with childhood or adolescent onset. AGL has three subclassifications: panniculitis (type 1), autoimmune disease (type 2), and idiopathic (type 3). This report highlights a rare case of AGL type 1 in a previously healthy 3-year-old female who presented with diffuse erythematous subcutaneous nodules, progressive lipoatrophy, and histopathological findings of a lobular panniculitis.

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http://dx.doi.org/10.1111/pde.15668DOI Listing

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