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| http://dx.doi.org/10.1186/s12967-024-05343-z | DOI Listing |
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Combined use of plasma p‐tau 181 and neurofilament light chain in Subjective Cognitive Decline and Mild Cognitive Impairment: future perspective and clinical applicability.
Alzheimers Dement
December 2024
Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Florence, Italy
Background: There is an urgent need to move the use of plasma biomarkers from research setting to clinical practice for the early detection of Alzheimer’s disease (AD). The aims of the study were to explore the combined use of plasma p‐tau181 and NfL in Subjective Cognitive Decline (SCD) and Mild Cognitive Impairment (MCI) patients, evaluating diagnostic accuracy and concordance to propose a flow chart for the clinical applicability.
Method: We included 43 SCD, 41 MCI and 21 AD‐dementia (AD‐d) patients, who underwent plasma p‐tau181 and NfL analysis with SiMoA assay.
Knowledge, Attitude, and Practices Regarding Leprosy Among Nurses Employed at a Tertiary Healthcare Centre in Central India: An Epidemiological Study.
Cureus
December 2024
Dermatology, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.
Introduction: Leprosy is a common infectious disease in India that can lead to nerve damage and disability. There is a dearth of knowledge regarding leprosy not only among the general public but also among healthcare workers. This knowledge gap leads to the generation of stigma and delay in the detection of new cases.
View Article and Find Full Text PDFThe Virtual Client Experience Survey for Mental Health and Addictions: Revalidation of a Survey to Measure Client and Family Experiences of Virtual Care.
J Med Internet Res
January 2025
Centre for Addiction and Mental Health, Toronto, ON, Canada.
Background: The onset of the COVID-19 pandemic precipitated a rapid shift to virtual care in health care settings, inclusive of mental health care. Understanding clients' perspectives on virtual mental health care quality will be critical to informing future policies and practices.
Objective: This study aimed to outline the process of redesigning and validating the Virtual Client Experience Survey (VCES), which can be used to evaluate client and family experiences of virtual care, specifically virtual mental health and addiction care.
Bacteriophage Receptor Recognition and Nucleic Acid Transfer.
Subcell Biochem
December 2024
Department of Macromolecular Structure, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
Correct host cell recognition is important in the replication cycle for any virus, including bacterial viruses. This essential step should occur before the bacteriophage commits to transferring its genomic material into the target bacterium. In this chapter, we will discuss the mechanisms and proteins bacteriophages use for receptor recognition (just before full commitment to infection) and nucleic acid injection, which occurs just after commitment.
View Article and Find Full Text PDFJaw Growth and Development in Class II Division I Malocclusion Children Using the Myobrace® Muscle Function Appliance.
Ann Ital Chir
December 2024
Department of Orthodontics, Dental Disease Prevention and Treatment Institute of Huangpu District, 200002 Shanghai, China.
Aim: Class II Division I malocclusion is common in pediatric orthodontics, and is often associated with malocclusion and poor muscle functionality. However, research on post-treatment changes in maxillomandibular dimensions, excluding normal development influences, is limited. Therefore, this study aimed to investigate the effects of Myobrace® appliance and targeted muscle functional training on maxillomandibular dimensions in children with Class II Division I malocclusion, compared to directed oral muscle training alone.
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