The dynamic world of the 8-17 DNAzyme.

Nat Commun

Heinrich Heine University, Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Düsseldorf, Germany.

Published: June 2024

DNA catalysts, known as DNAzymes, have arguably been limited for decades by the lack of mechanistic information. The solution structure of the 8–17 DNAzyme reported by Wieruszekska, Pwlowicz et al. reassesses the current thinking regarding the relationship between structure, dynamic, and metal ion coordination.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11183194PMC
http://dx.doi.org/10.1038/s41467-024-49500-wDOI Listing

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