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Spectral properties of bursts in therapeutic burst suppression predict successful treatment of refractory status epilepticus.
Epilepsy Behav
December 2024
Epilepsy Center, Department of Neurology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany. Electronic address:
Burst suppression (BS) on EEG induced by intravenous anesthesia (IVAT) is standard therapy for refractory status epilepticus (RSE). If BS has any independent therapeutic effect on RSE is disputed. We aimed to define EEG characteristics of BS predicting termination or recurrence of status after weaning.
View Article and Find Full Text PDFOvercoming age: Slow anesthesia induction may prevent geriatric patients from developing burst suppression and help developing intraoperative EEG signatures of a younger brain.
J Clin Anesth
December 2024
Department of Anesthesiology and Intensive Care Medicine, Technical University of Munich School of Medicine and Health, Munich, Germany. Electronic address:
Elderly patients are prone to develop postoperative neurocognitive deficits potentially precipitated by inadequate anesthetic management. To investigate the potential of EEG-guided individualized anesthetic titration we evaluated the effect of the patient's age on the spectral composition of the EEG during slow propofol induction. Twenty-six young (<65 years) and 25 old (≥65 years) patients received propofol until loss of responsiveness (LOR).
View Article and Find Full Text PDFThe Utility of Electroencephalograhy in Guiding General Anesthesia in Children.
Anesth Analg
October 2024
Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Article Synopsis
- Traditional pediatric anesthetic dosing based on age and weight can lead to oversedation; intraoperative electroencephalography (EEG) helps optimize drug doses by monitoring brain activity in real time.
- EEG-guided anesthesia aims to maintain an optimal state of hypnosis while minimizing adverse effects, particularly for children with complex anesthetic needs.
- The review highlights the benefits of EEG monitoring, including possible reductions in anesthetic dosage, prevention of EEG suppression, and fewer peri-operative complications.
For EEG-Guided Anesthesia, We Have to Go Beyond the Index.
Anesth Analg
September 2024
Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Palo Alto, California.
Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac Surgery: The ENGAGES-Canada Randomized Clinical Trial.
JAMA
July 2024
Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri.
Article Synopsis
- Intraoperative EEG suppression during anesthesia can indicate excessive sedation and has been linked to higher rates of postoperative delirium, particularly after cardiac surgeries.
- A randomized clinical trial involving 1140 adults aged 60 and older investigated if EEG-guided anesthesia could reduce the incidence of delirium compared to usual anesthesia care.
- Results showed that there was no significant difference in postoperative delirium rates (around 18%) between the EEG-guided group and the usual care group, despite lower anesthetic doses and less time spent in EEG suppression in the EEG-guided group.
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