AI Article Synopsis

  • Pulmonary nodules are common in lung-related medical practice, with causes ranging from infection to cancer, and an unusual condition known as placental transmogrification of the lung (PLC) being exceedingly rare.
  • PLC typically presents as single lesions in asymptomatic males, but this case is unique as it involves a young female with bilateral nodules.
  • The identified nodules in this patient were larger than typical PLC cases and demonstrated growth over an 8-year period, which is uncommon for this condition.

Article Abstract

Pulmonary nodules are commonly encountered in pulmonary practice. Etiologies could include infectious, inflammatory, and malignant. Placental transmogrification of the lung is an extremely rare etiology of pulmonary nodules. Such condition often presents as unilateral lesions in asymptomatic men. In general, such nodules are generally stable and grow extremely slowly. We highlight an unusual case of placental transmogrification of the lung (PLC) identified in a young female. The patient's bilateral nodules were larger than what has been previously cited in the literature and exhibited growth over an 8-year follow-up period.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11185031PMC
http://dx.doi.org/10.1177/23247096241261322DOI Listing

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Article Synopsis
  • Pulmonary nodules are common in lung-related medical practice, with causes ranging from infection to cancer, and an unusual condition known as placental transmogrification of the lung (PLC) being exceedingly rare.
  • PLC typically presents as single lesions in asymptomatic males, but this case is unique as it involves a young female with bilateral nodules.
  • The identified nodules in this patient were larger than typical PLC cases and demonstrated growth over an 8-year period, which is uncommon for this condition.
View Article and Find Full Text PDF

Placental transmogrification of the lung (PTL) is a rare pulmonary condition characterized by the presence of immature placental villous structures. The etiology and molecular mechanisms underlying this disease remain largely unknown. This functional study aimed to identify the molecular signatures in the pathogenesis of PTL via comprehensive transcriptome analysis.

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