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Atmospheric particulate matter and hypoxaemia in Korean children receiving general anaesthesia: A retrospective analysis. | LitMetric

Atmospheric particulate matter and hypoxaemia in Korean children receiving general anaesthesia: A retrospective analysis.

Eur J Anaesthesiol

From the Department of Anaesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea (J-BP, PK, S-HJ, Y-EJ, J-HL, J-TK, H-SK, E-HK).

Published: September 2024

AI Article Synopsis

  • The study aimed to explore the link between levels of atmospheric particulate matter on surgery day and instances of intra-operative hypoxaemia (low oxygen levels) in children under general anaesthesia.
  • It was conducted retrospectively at a single center, analyzing data from children aged 18 or younger who underwent surgeries from January 2019 to October 2020, with air quality data sourced from public records.
  • Results indicated that higher levels of particulate matter (≥81 μg m -3) were associated with an increased risk of hypoxaemia during surgery, suggesting air pollution could impact children's health during medical procedures.

Article Abstract

Background: The association between the concentration of atmospheric particulate matter on the day of surgery and the occurrence of intra-operative hypoxaemia in children receiving general anaesthesia is unclear.

Objective: To investigate the association between the exposure to particulate matter on the day of surgery and the occurrence of intra-operative hypoxaemia, defined as a pulse oximetry oxygen saturation of less than 90% for more than 1 min, in children.

Design: Retrospective study.

Setting: Single-centre.

Participants: Children aged 18 years or younger who received general anaesthesia between January 2019 and October 2020.

Intervention: Information on daily levels of particulate matter with a diameter 10 μm or less and 2.5 μm or less measured within a neighbourhood corresponding to the area defined by the hospital's zip code was obtained from publicly available air-quality data.

Main Outcome Measures: The primary outcome was intra-operative hypoxaemia, defined as a pulse oximetry oxygen saturation of less than 90% lasting for more than 1 min, manually verified by anaesthesiologists using vital sign registry data extracted at 2 s intervals.

Results: Of the patients finally analysed, 3.85% (489/13 175) experienced intra-operative hypoxaemia. Higher levels of particulate matter 10 μm or less in diameter (≥81 μg m -3 , 17/275, 6.2%) were associated with an increased occurrence of intra-operative hypoxaemia compared with lower particulate matter concentrations [<81 μg m -3 , 472/12 900, 3.7%; adjusted odds ratio, 1.71; 95% confidence interval (CI), 1.04 to 2.83; P  = 0.035].

Conclusion: The level of particulate matter on the day of surgery pose a risk of intra-operative hypoxaemia in children receiving general anaesthesia. If the concentrations of particulate matter 10 μm or less in diameter on the day of surgery are high, children receiving general anaesthesia should be managed with increased caution.

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Source
http://dx.doi.org/10.1097/EJA.0000000000002027DOI Listing

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