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Elevated neutrophil-to-hemoglobin ratio as an indicator of poor survival in hepatitis B virus-related decompensated cirrhosis. | LitMetric

Elevated neutrophil-to-hemoglobin ratio as an indicator of poor survival in hepatitis B virus-related decompensated cirrhosis.

Biomark Med

Department of Clinical Laboratory, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China.

Published: July 2024

AI Article Synopsis

  • - The study investigated how the neutrophil-to-hemoglobin ratio (NHR) can predict mortality in patients with HBV-related decompensated cirrhosis (HBV-DC), enrolling 172 participants.
  • - Results showed a 30-day mortality rate of 12.8%, with those who did not survive having a significantly higher NHR compared to survivors.
  • - NHR and the MELD score were identified as the main independent predictors of mortality, with NHR's predictive ability being comparable to that of the MELD score, indicating its potential use as an accessible mortality indicator.

Article Abstract

Our goal was to explore the prognostic value of the neutrophil-to-hemoglobin ratio (NHR) in HBV-related decompensated cirrhosis (HBV-DC) patients. 172 HBV-DC patients were enrolled. Multivariate analyses were used to identify risk factors influencing 30-day mortality. The 30-day mortality was 12.8% (22/172). nonsurvivors exhibited a higher NHR than survivors. On multivariate analysis, NHR and model for end-stage liver disease (MELD) score were the only independent predictors of mortality. Notably, the predictive capabilities of NHR were found to be comparable to those of the MELD score. High NHR was associated with poor prognosis in HBV-DC patients, and NHR can serve as an effective and readily available indicator for the prediction of mortality in these patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285354PMC
http://dx.doi.org/10.1080/17520363.2024.2352420DOI Listing

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