Dimesulfazet can control annual and perennial sedges in rice paddies. Here we assessed its mode of action. We performed a phenotype assay of , conducted a metabolomic analysis of , and analyzed the endogenous concentration of very long-chain fatty acids (VLCFAs) in . Dimesulfazet treatment caused curling and greening symptoms in the leaves and -like symptoms in the inflorescences of . These symptoms were visually indistinguishable from those caused by flufenacet and benfuresate, which belong to Herbicide Resistance Action Committee (HRAC) Group 15. We performed GC-MS/MS analysis of primary metabolites and LC-MS analysis of lipids in the herbicide-treated , followed by Orthogonal Partial Least Squares Discriminant Analysis clustering. The results showed that dimesulfazet belongs to the HRAC Group 15 cluster. The endogenous concentrations of C24:0, C26:0, and C28:0 decreased in dimesulfazet-treated plants as compared to those in the control. Overall, the mode of action of dimesulfazet involves the inhibition of VLCFA biosynthesis.
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| http://dx.doi.org/10.1584/jpestics.D23-036 | DOI Listing |
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