Dry scooping, a rather risky act of consuming undiluted pre-workout protein powder hoping for a more pronounced energy surge, is increasingly becoming a fitness trend worldwide. A previously healthy 25-year-old man of African origin presented with acute onset of crushing mid-sternal chest pain for 4 h. His symptoms began about an hour following completion of his 2-h exercise regimen at the gym. He had an unremarkable past medical history except for an 8-month consumption of a pre-workout supplement as part of his gym routine. He claimed to have adhered to the manufacturer's recommended method of using the supplement, except for 3 days prior to presentation when he started "dry scooping" following the viewing of a video advocating such practice from his fitness WhatsApp group. Cardiac evaluation revealed features in keeping with diagnosis of anterolateral ST-elevation myocardial infarction. Emergency coronary angiography revealed a thrombotic lesion completely occluding the proximal left anterior descending coronary artery with TIMI 0 flow distally. After successful balloon angioplasty, a drug-eluting stent was implanted successfully, restoring TIMI 3 flow to the proximal left anterior descending coronary artery. This case report aims to raise awareness among both clinicians and the general public regarding the pervasiveness of pre-workout supplements, improper methods of consumption, and the potential life-threatening repercussions of misuse.
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http://dx.doi.org/10.1177/2050313X241261157 | DOI Listing |
Front Biosci (Landmark Ed)
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Department of Cardiology, Affiliated Hospital of Jiangnan University, 214122 Wuxi, Jiangsu, China.
Background: Myocardial ischemia-reperfusion (I/R) injury refers to cell damage that occurs as a consequence of the restoration of blood circulation following reperfusion therapy for cardiovascular diseases, and it is a primary cause of myocardial infarction. The search for nove therapeutic targets in the context of I/R injury is currently a highly active area of research. p70 ribosomal S6 kinase (S6K1) plays an important role in I/R induced necrosis, although the specific mechanisms remain unclear.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
January 2025
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, 401336 Chongqing, China.
Background: Myocardial ischemia-reperfusion (I/R) injury and coronary microcirculation dysfunction (CMD) are observed in patients with myocardial infarction after vascular recanalization. The antianginal drug trimetazidine has been demonstrated to exert a protective effect in myocardial ischemia-reperfusion injury.
Objectives: This study aimed to investigate the role of trimetazidine in endothelial cell dysfunction caused by myocardial I/R injury and thus improve coronary microcirculation.
J Investig Med High Impact Case Rep
January 2025
LSU Health Shreveport, LA, USA.
An 18-year-old teenager with significant atherosclerotic cardiovascular disease (ASCVD) risk factors developed acute chest pain. His electrocardiogram showed inferior ST-segment elevations. Emergent coronary angiogram revealed complete thrombotic occlusion of the right coronary artery.
View Article and Find Full Text PDFJ Clin Med
January 2025
Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, Bronx, New York, NY 10467, USA.
Primary percutaneous coronary intervention (PCI) has revolutionized the management of ST-elevation myocardial infarction (STEMI), markedly improving patient outcomes. Despite technological advancements, pharmacological innovations, and refined interventional techniques, STEMI prognosis remains burdened by a persistent incidence of cardiac death and heart failure (HF), with mortality rates plateauing over the last decade. This review examines current practices in primary PCI, focusing on critical factors influencing patient outcomes.
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January 2025
Department of Cardiology, Angiology and Intensive Care, Philipps University Marburg, 35043 Marburg, Germany.
Emerging evidence suggests the role of mechanical circulatory support (MCS) devices in the therapy of refractory cardiogenic shock (CS). However, largerandomized trials addressing the role of Impella in the therapy of infarct-associated CS are sparse. As such, evidence coming from comprehensive retrospective studies or meta-analyses is of major importance in order to clarify the role of the Impella device in this setting.
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