Alpha-gal IgE level can change rapidly. Reassessment of a patient's alpha-gal IgE level may be helpful in the patient's clinical follow-up. Pruritus related to the site of a previous tick bite strengthens the diagnosis of alpha-gal syndrome.
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http://dx.doi.org/10.1016/j.jacig.2024.100280 | DOI Listing |
Yonsei Med J
January 2025
Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea.
Screening tests for specific immunoglobulin E (sIgE) to food allergens, such as the multiple allergen simultaneous test (MAST), are widely used in patients with suspected food allergies in South Korea. We evaluated whether MAST could effectively screen wheat-dependent exercise-induced anaphylaxis (WDEIA) and α-gal syndrome (AGS). We retrospectively reviewed patients with WDEIA and AGS diagnosed with unequivocal history and positive sIgE results for omega-5 gliadin and α-gal using ImmunoCAP, respectively.
View Article and Find Full Text PDFFront Allergy
December 2024
Deptartment of Dermatology, University of Zurich & University Hospital Zurich, Zurich, Switzerland.
J Clin Med
November 2024
Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
: IgE to galactose-alpha-1,3-galactose (alpha-gal) is associated with (lone star tick) bites, accounting for the regional distribution of the alpha-gal syndrome (AGS). Longitudinal studies describing risk factors for incident alpha-gal sensitization are lacking. The objective of this project was to assess the incidence of alpha-gal IgE seroconversion and identify associated demographic, occupational, and geographical risk factors among US military personnel.
View Article and Find Full Text PDFAnn Med Surg (Lond)
December 2024
Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, Bangladesh.
Crit Care Nurs Q
December 2024
Author Affiliations: Atlantic Health System, Morristown Medical Center, Morristown, New Jersey (Silbernagel); and Novant Health New Hanover Regional Medical Center, Wilmington, North Carolina (Bullard).
Alpha-gal syndrome is a serious, potentially life-threatening allergic reaction to mammalian products that has been linked to the lone star tick. Early recognition and management of alpha-gal syndrome is key for desirable patient outcomes and informed nursing care can make all the difference. The purpose of this article is to provide background information regarding alpha-gal syndrome, review common sources of potential reaction triggers including food and medications, and discuss strategies to detect and avoid allergic reactions from occurring.
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