Pellagra: Is It Here or is It Rare?

J Assoc Physicians India

Co-Chairman and Senior Consultant, Department of Internal Medicine, Sir Ganga Ram Hospital, Delhi, India.

Published: May 2024

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http://dx.doi.org/10.59556/japi.72.0533DOI Listing

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Pellagra, a rare disorder caused by niacin deficiency, manifests as 4Ds: dermatitis, diarrhea, dementia, and, if left untreated, death. Though it was thought to be eradicated from the United States after fortification with niacin, there have been concerns about its reemergence in specific high-risk populations such as chronic alcoholism, malabsorption, and anorexia nervosa. Here we present a patient with altered mental status who subsequently developed diarrhea during the course of hospitalization.

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Pellagra: Is It Here or is It Rare?

J Assoc Physicians India

May 2024

Co-Chairman and Senior Consultant, Department of Internal Medicine, Sir Ganga Ram Hospital, Delhi, India.

View Article and Find Full Text PDF
Article Synopsis
  • - This report details a rare case of pellagra in a 60-year-old man with a history of chronic alcoholism, showcasing symptoms like a rash and diarrhea.
  • - Laboratory tests showed significant niacin deficiencies, confirming the diagnosis, and initiating niacin supplements and dietary changes improved the patient's condition.
  • - The case highlights the importance of recognizing the classic symptoms of pellagra—rash, diarrhea, and malnutrition—especially in individuals with alcohol use disorder for better health outcomes.
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