AI Article Synopsis
- The study investigates how effective MR morphometry is in localizing focal cortical dysplasias (FCD) in children with drug-resistant epilepsy after surgery.
- It involved 13 children whose MR data was independently assessed by three radiologists, comparing traditional visual analysis with MR morphometry.
- Results showed that MR morphometry detected FCD more accurately and identified signs like gray-white matter blurring that were often overlooked by radiologists.
Article Abstract
Objective: Assessing the diagnostic significance of MR morphometry in determining the localization of focal cortical dysplasias (FCD).
Material And Methods: The study included 13 children after surgery for drug-resistant epilepsy caused by FCD type II and stable postoperative remission of seizures (Engel class IA, median follow-up 56 months). We analyzed the results of independent expert assessment of native MR data by three radiologists (HARNESS protocol) and MR morphometry data regarding accuracy of FCD localization. We considered 2 indicators, i.e. local cortical thickening and gray-white matter blurring.
Results: FCD detection rate was higher after MR morphometry compared to visual analysis of native MR data using the HARNESS protocol. MR morphometry also makes it possible to more often identify gray-white matter blurring as a sign often missed by radiologists (<0.05).
Conclusion: MR morphometry is an additional non-invasive method for assessing the localization of FCD.
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| http://dx.doi.org/10.17116/neiro20248803145 | DOI Listing |
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