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Objectives: We aimed to assess the anti-mutated citrullinated vimentin (anti-MCV) antibodies in RA patients' serum and to explore their association with interstitial lung disease (ILD).
Methods: Eighty rheumatoid arthritis (RA) patients and forty healthy controls were included in this case-control study. Of these patients, forty had ILD, and forty without ILD.
Genetic factors shaping the plasma lipidome and the relations to cardiometabolic risk in children and adolescents.
EBioMedicine
January 2025
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address:
Background: Lipid species are emerging as biomarkers for cardiometabolic risk in both adults and children. The genetic regulation of lipid species and their impact on cardiometabolic risk during early life remain unexplored.
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Knight Alzheimer Disease Research Center, St. Louis, MO, USA.
Background: The ability to detect cognitive impairment from Alzheimer Disease (AD) in its earliest possible symptomatic stage is a highly desirable characteristic for neuropsychological measures. Because early cognitive changes are often subtle, measures with high sensitivity are of great importance. Variability in attention, often assessed using reaction time (RT) tasks, have been shown to discriminate between cognitively normal older individuals with and without positive AD biomarkers and is correlated with biological markers of neurodegeneration.
View Article and Find Full Text PDFIntroduction: Out-of-hospital cardiac arrest (OHCA) is a critical condition associated with high mortality rates and neurological impairment among survivors. In comatose OHCA patients who achieve return of spontaneous circulation, early risk stratification is important to inform treatment pathways and potentially improve outcomes. A range of prognostic tools have been developed to predict survival and neurological recovery.
View Article and Find Full Text PDFRisk Factors and Predictive Accuracy of the Rotterdam Risk Index for Wound Dehiscence Following Abdominal Surgery.
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General Internal Medicine, Luton and Dunstable University Hospital, Luton, GBR.
Background Wound dehiscence (WD) is a major postoperative complication following abdominal surgeries, particularly exploratory laparotomy. Identifying preoperative risk factors and using predictive tools, such as the Rotterdam Risk Index (RRI), are crucial for early intervention and improving patient outcomes. This study aimed to evaluate the risk factors associated with WD and assess the predictive accuracy of the RRI in a cohort of patients undergoing abdominal surgeries.
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