Subperiosteal hematoma as a rare complication of neurofibromatosis 1: A case report and review of the literature.

Introduction: Subperiosteal hematoma (SPH) is a rare complication of neurofibromatosis type 1 (NF-1) which can be presented spontaneously or after a minor trauma a painful or painless growing lesion.

Presentation Of Case: Here, we presented a 10-year-old boy, a known case of NF-1, who presented with a painless growing leg lesion. The bony wall cystic lesion was suggested based on radiologic and pathologic investigation. During the operation, an SPH was detected and excised completely.

Discussion: Consistent with previous reports, our case of subperiosteal hematoma in an NF-1 patient predominantly presented with well-established subperiosteal bone proliferation on plain radiographs, with the hematoma most commonly affecting the tibia.

Conclusion: The SPH in NF-1 and differentiating it from a malignant transformation should be considered for the rapidly enlarging bony mass.