Background: Chronic cough (CC) affects about 10% of adults, but opioid use in CC is not well understood.
Objectives: To determine the use of opioid-containing cough suppressant (OCCS) prescriptions in patients with CC using electronic health records.
Design: Retrospective cohort study.
Methods: Through retrospective analysis of Midwestern U.S. electronic health records, diagnoses, prescriptions, and natural language processing identified CC - at least three medical encounters with cough, with 56-120 days between first and last encounter - and a 'non-chronic cohort'. Student's -test, Pearson's chi-square, and zero-inflated Poisson models were used.
Results: About 20% of 23,210 patients with CC were prescribed OCCS; odds of an OCCS prescription were twice as great in CC. In CC, OCCS drugs were ordered in 38% with Medicaid insurance and 15% with commercial insurance.
Conclusion: Findings identify an important role for opioids in CC, and opportunity to learn more about the drugs' effectiveness.
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http://dx.doi.org/10.1177/17534666241259373 | DOI Listing |
BMJ Case Rep
January 2025
Pulmonary Medicine, Siksha O Anusandhan University Institute of Medical Sciences and SUM Hospital, Bhubaneswar, Orissa, India.
Tuberculosis (TB) is a great mimicker due to its various unusual and atypical presentations. Mass-like lesions in thoracic radiology may raise the suspicion of lung malignancy. A man in his early 50s complained of cough, low-grade fever and dyspnoea.
View Article and Find Full Text PDFPLoS Negl Trop Dis
January 2025
Department of Radiology, Assam Medical College & Hospital, Dibrugarh, Assam, India.
Background: Chronic pulmonary aspergillosis (CPA) is a disease commonly caused by Aspergillus fumigatus and other Aspergillus species characterized by cavitary lung lesions. Tea garden population is an agrarian population of Assam, mostly associated with tea plantations. Assam is a major tea-producing state with 803 tea gardens producing approximately 50% of the total tea in India, of which 177 are present in the Dibrugarh district alone.
View Article and Find Full Text PDFPLoS One
January 2025
School of Rehabilitation Science, Faculty of Health Science, McMaster University, Hamilton, Ontario, Canada.
Introduction: Characteristics of chronic obstructive pulmonary disease (COPD) can include shortness of breath, chronic cough, sputum production and reduced exercise capacity. The sit-to-stand (STS) test variations (e.g.
View Article and Find Full Text PDFAm J Case Rep
January 2025
Department of Pulmonary and Critical Care Medicine, Faculty and Graduate School of Medicine, Mie University, Tsu, Mie, Japan.
BACKGROUND Pembrolizumab, a programmed cell-death protein-1 (PD-1)-targeting antibody, extends survival in cancer patients but may cause lung injury as a side effect. This immunotherapy enhances the immune system's ability to recognize and eliminate cancer cells. However, its immunomodulatory action can sometimes lead to immune-related adverse events, including lung injury.
View Article and Find Full Text PDFAm J Dent
December 2024
Department of Prosthodontics and Periodontics, University of São Paulo (USP), Bauru, Brazil,
Purpose: This mini-review discusses the clinical implication of respiratory pathogens in the biofilm on acrylic resin removable dentures in the elderly.
Methods: A search was conducted using the keywords: "dentures", " acrylic resin", "biofilm", "pneumonia", "elderly", "respiratory pathogens", and "respiratory diseases" in databases PubMed/Medline, Lilacs, SciELO and textbooks between 1999 and 2024.
Results: The elderly are more susceptible to chronic diseases and/or life-threatening infections because of senescence itself and functional and degenerative alterations.
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