Predicting brain age using Tri-UNet and various MRI scale features.

Sci Rep

School of Information Science and Technology, Beijing Forestry University, Beijing, 100083, China.

Published: June 2024

In the process of human aging, significant age-related changes occur in brain tissue. To assist individuals in assessing the degree of brain aging, screening for disease risks, and further diagnosing age-related diseases, it is crucial to develop an accurate method for predicting brain age. This paper proposes a multi-scale feature fusion method called Tri-UNet based on the U-Net network structure, as well as a brain region information fusion method based on multi-channel input networks. These methods address the issue of insufficient image feature learning in brain neuroimaging data. They can effectively utilize features at different scales of MRI and fully leverage feature information from different regions of the brain. In the end, experiments were conducted on the Cam-CAN dataset, resulting in a minimum Mean Absolute Error (MAE) of 7.46. The results demonstrate that this method provides a new approach to feature learning at different scales in brain age prediction tasks, contributing to the advancement of the field and holding significance for practical applications in the context of elderly education.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178849PMC
http://dx.doi.org/10.1038/s41598-024-63998-6DOI Listing

Publication Analysis

Top Keywords

brain age
12
predicting brain
8
fusion method
8
feature learning
8
brain
7
age tri-unet
4
tri-unet mri
4
mri scale
4
scale features
4
features process
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!