Introduction: To explore the association between magnesium depletion score (MgDS) and the prevalence of kidney stones in the low primary income ratio (PIR).
Method: A cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey 2007-2018. Within the low PIR, people aged ≥20 years with complete information on MgDS and kidney stones questionnaires were enrolled. Multivariable logistic regression and stratified logistic regression analyses were performed to examine the association between MgDS and the prevalence of kidney stones and the recurrence of kidney stones by confounding factors adjusted. Stratified and interaction analysis was conducted to find whether some factors modified the association. In addition, sensitive analyses were also conducted to observe the stability. The work has been reported in line with the strengthening the reporting of cohort, cross-sectional, and case-control studies in surgery (STROCSS) criteria (Supplemental Digital Content 1, http://links.lww.com/JS9/C781 ).
Result: A total of 7600 adults were involved in the study, and the individuals were classified into four groups: 0 points for MgDS ( n =3814), 1 point for MgDS ( n =2229), 2 points for MgDS ( n =1020), and ≥3 points for MgDS ( n =537). The multivariable logistic regression suggested that a positive association between MgDS and the prevalence of kidney stones (OR=1.123, 95% CI: 1.019-1.238) in the fully adjusted model. Compared with the lowest group, people with ≥3 points of MgDS had a significant relationship with kidney stones (OR=1.417, 95% CI: 1.013-1.983). No significant association was observed between the recurrence of kidney stones and MgDS. The result of the sensitive analysis showed the robustness of the main analysis.
Conclusion: The prevalence of kidney stones is positively correlated with MgDS, which suggests that maintaining a higher MgDS is accompanied by higher prevalence rates of kidney stones in the low PIR.
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http://dx.doi.org/10.1097/JS9.0000000000001822 | DOI Listing |
Medicine (Baltimore)
January 2025
Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
This study explores the relationship between 25-hydroxyvitamin D/calcium/alkaline phosphatase (ALP) levels and kidney stone development via cross-sectional and Mendelian randomization (MR) analyses. We used data from the National Health and Nutrition Examination Survey (NHANES) 2013 to 2018 to explore the associations of 25(OH)D metabolite, calcium, and ALP levels with kidney stone development, LDSC analysis to determine the associations between their genetically predicted levels and kidney stone development, and MR analysis to determine the causality of those relationship via genome-wide association studies (GWASs). The cross-sectional study revealed a relationship between ALP levels and kidney stone development (Model 1: OR = 1.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Urology, Suzhou Wuzhong No.2 People's Hospital, Suzhou, China.
Background: This study investigates the relationship between sagittal abdominal diameter (SAD), a measure of abdominal obesity, and kidney stone disease (KSD) in the U.S. population.
View Article and Find Full Text PDFDiseases
January 2025
Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84016 Pagani, Italy.
Background: Fatigue is a prevalent and complex condition with significant impacts on well-being. Existing fatigue assessments often lack comprehensiveness or practicality for general population studies.
Methods: This study validated the REST Questionnaire, a novel fatigue assessment tool, in a sample of 268 adults.
Diseases
January 2025
Department of Urology, Kanazawa Medical University, Uchinada 920-0293, Ishikawa, Japan.
Urinary stones (urolithiasis) have been categorized as kidney stones (renal calculus), ureteric stones (ureteral calculus and ureterolith), bladder stones (bladder calculus), and urethral stones (urethral calculus); however, the mechanisms underlying their promotion and related injuries in glomerular and tubular cells remain unclear. Although lifestyle-related diseases (LSRDs) such as hyperglycemia, type 2 diabetic mellitus, non-alcoholic fatty liver disease/non-alcoholic steatohepatitis, and cardiovascular disease are risk factors for urolithiasis, the underlying mechanisms remain unclear. Recently, heat shock protein 90 (HSP90) on the membrane of HK-2 human proximal tubular epithelium cells has been associated with the adhesion of urinary stones and cytotoxicity.
View Article and Find Full Text PDFBJU Int
January 2025
Department of Urology, University of Alabama, Birmingham, AL, USA.
Objectives: To identify associations between 24-h urine abnormalities and clinical risk factors for recurrent stone formers.
Patients And Methods: The Registry for Stones of the Kidney and Ureter was queried for all patients who underwent 24-h urine studies. Patients were categorised by the number of clinical risk factors for recurrent stone disease.
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