AI Article Synopsis

  • * Post-2019 samples included 32 strains that carried new genetic features linked to resistance.
  • * Phylogenetic analysis showed three sub-lineages of carbapenem-resistant strains primarily from Ukraine and Georgia, including a significant epidemic clone with all three key resistance genes, highlighting the need for effective infection control and global monitoring.

Article Abstract

In 2003-2023, amid 5,436 isolates collected globally through the Multidrug-Resistant Organism Repository and Surveillance Network, 97 were ST19PAS, 34 of which carbapenem-resistant. Strains (n = 32) sampled after 2019 harboured either , , and/or . Phylogenetic analysis of the 97 isolates and 11 publicly available ST19 genomes revealed three sub-lineages of carbapenemase-producing isolates from mainly Ukraine and Georgia, including an epidemic clone carrying all three carbapenemase genes. Infection control and global surveillance of carbapenem-resistant remain important.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11177571PMC
http://dx.doi.org/10.2807/1560-7917.ES.2024.29.24.2400259DOI Listing

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