The hands are the most complex organs of the body for performing various activities. Therefore, it is critical to protect them against dangers. Protective gloves can reduce or prevent injuries, but they can downgrade hand performance in various aspects, including tactile sensitivity, strength, grip force and hand dexterity. In this study, eight protective gloves with different designs and materials were made. The study investigated the influence of the number of layers and several characteristics, e.g., mass per square meter, thickness, bending stiffness and compressibility, on the gloved hand performance regarding protection ability, tactile sensitivity, strength capability and manual dexterity. The results indicated that despite the improving effects of increasing layer thickness, weight, bending energy and compressibility on protection ability, the gloves diminish tactile sensitivity, grip and pinch force, and manual dexterity. Therefore, it is necessary to select an optimum design to ensure a satisfactory trade-off between protection and performance.
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