At least 1-2% of DNA sequences annotated as Blastocystis in GenBank represent organisms other than Blastocystis or sequence artefacts. As well as being biologically incorrect, such practice can lead to overestimates of genetic diversity, underestimated host specificity, and incorrect classification of samples tested for Blastocystis using DNA-based methods.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pt.2024.06.001DOI Listing

Publication Analysis

Top Keywords

minimizing second-generation
4
second-generation mis-identification
4
blastocystis
4
mis-identification blastocystis
4
blastocystis 1-2%
4
1-2% dna
4
dna sequences
4
sequences annotated
4
annotated blastocystis
4
blastocystis genbank
4

Similar Publications

The development of narrowband emissive, bright, and stable solution-processed organic light-emitting diodes (SP-OLEDs) remains a challenge. Here, a strategy is presented that merges within a single emitter a TADF sensitizer responsible for exciton harvesting and an MR-TADF motif that provides bright and narrowband emission. This emitter design also shows strong resistance to aggregate formation and aggregation-cause quenching.

View Article and Find Full Text PDF

Lumateperone is a novel antipsychotic recently approved for the treatment of schizophrenia. Its unique pharmacological profile includes modulation of serotonergic, dopaminergic, and glutamatergic neurotransmission, differentiating it from other second-generation antipsychotics. This paper explores the pharmacological features and clinical potential of lumateperone across neuropsychiatric conditions.

View Article and Find Full Text PDF

Biotechnology Revolution Shaping the Future of Diabetes Management.

Biomolecules

December 2024

Discipline of Microbiology, Department XIV Microbiology, University of Medicine and Pharmacy from Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.

Diabetes mellitus (DM) has a millennia-long history, with early references dating back to ancient Egypt and India. However, it was not until the 20th century that the connection between diabetes and insulin was fully understood. The sequencing of insulin in the 1950s initiated the convergence of biotechnology and diabetes management, leading to the development of recombinant human insulin in 1982.

View Article and Find Full Text PDF
Article Synopsis
  • Diabetic foot ulcers (DFUs) can lead to severe complications like amputation if not treated promptly, often due to delays in care.
  • A 56-year-old patient experienced a DFU linked to a bacterial infection from poultry exposure, requiring multiple debridement surgeries and targeted antibiotic treatment.
  • Effective management of DFUs involves adjusting antibiotic therapies based on identified pathogens to reduce mortality and prevent irreversible amputations.
View Article and Find Full Text PDF

The prognostic impact of 1q21 gain/amplification in newly diagnosed multiple myeloma: a retrospective study based on a single center in China.

Ann Hematol

January 2025

Department of Hematology, Beijing Chaoyang Hospital, Myeloma Research Center of Beijing, Capital Medical University, Gongtinanlu No 8, Chaoyang District, Beijing, 100020, China.

1q21gain/amp is the most common in patients with multiple myeloma. However, there is limited research on the prognostic heterogeneity of 1q21+, and the prognostic of the 1q21 copy remains controversial. In this study, we primarily conducted a retrospective analysis of the prognostic significance of 1q21 gain/amp in 375 newly diagnosed multiple myeloma patients.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!