AI Article Synopsis

  • This study compares the effectiveness and safety of two stent systems, Neuroform Atlas and LVIS Jr, in treating unruptured intracranial aneurysms in small parent arteries (less than 2mm).
  • A total of 135 patients were analyzed from March 2022 to April 2023, focusing on factors like stent placement success, aneurysm blockage, and any complications that arose.
  • Results showed that the LVIS Jr stent had a higher rate of incomplete placement and complications, with specific stent angles and parent artery size discrepancies identified as risk factors for poor outcomes.

Article Abstract

Background And Purpose: The Neuroform Atlas stent and the LVIS Jr stent are intracranial microstent systems for the treatment of wide-neck intracranial aneurysms. Hence, this study aimed to compare the efficacy and safety of the Neuroform Atlas stent and the LVIS Jr stent for the treatment of unruptured intracranial aneurysms in parent arteries of <2 mm in diameter.

Materials And Methods: From March 2022 to April 2023, the clinical and imaging data of 135 patients with unruptured intracranial aneurysms treated with stent-assisted coiling using the Neuroform Atlas or LVIS Jr stent in parent arteries of <2 mm in diameter were retrospectively analyzed. Stent apposition was evaluated by high-resolution conebeam CT (HR-CBCT). Immediate aneurysm-embolization attenuation and occlusion at 6-month follow-up were evaluated using 2D DSA and the modified Raymond-Roy classification. Adverse events were recorded. Multivariate logistic regression analysis was undertaken to determine the independent factors affecting incomplete stent apposition.

Results: One hundred thirty-five patients (135 aneurysms) underwent stent-assisted coiling (66 Neuroform Atlas stents and 69 LVIS Jr stents). Intraoperative HR-CBCT showed that 1 Neuroform Atlas stent and 11 LVIS Jr stents had incomplete stent apposition at the aneurysm neck (< .05). Perioperative complications occurred in 3 cases (2.22%). These comprised 2 cases of neurologic complications (1 case of distal intracranial vascular embolism and 1 case of cerebral parenchymal hemorrhage) and 1 case of severe postprocedural gastrointestinal hemorrhage. DSA follow-up showed 3 cases of aneurysm recurrence in the LVIS Jr group. Multivariate regression analysis showed that a stent angle of ≥75° (OR, 23.963; = .005) or a parent artery diameter mismatch ratio of ≥1.25 (OR, 8.043; = .037) were risk factors for incomplete stent apposition, especially for the LVIS Jr stent (OR, 20.297; = .015).

Conclusions: The Neuroform Atlas stent and LVIS Jr stent are efficacious in the treatment of unruptured intracranial aneurysms in parent arteries of <2 mm in diameter. Apposition of the LVIS Jr stent was worse than in the Neuroform Atlas stent at the neck of some aneurysms.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11286018PMC
http://dx.doi.org/10.3174/ajnr.A8238DOI Listing

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