In this issue of Cell Host & Microbe, Shang et al. identify murine neuropilin 1 as a host factor that binds reovirus particles, directing cell entry and contributing to viral dissemination and neurovirulence. This study highlights the reovirus model system to investigate host receptors and their significance in viral pathogenesis.
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Neuropilin invites reoviruses into neurons.
Cell Host Microbe
June 2024
Department of Microbiology and Immunology, Loyola University Chicago, Maywood, IL 60153, USA. Electronic address:
In this issue of Cell Host & Microbe, Shang et al. identify murine neuropilin 1 as a host factor that binds reovirus particles, directing cell entry and contributing to viral dissemination and neurovirulence. This study highlights the reovirus model system to investigate host receptors and their significance in viral pathogenesis.
View Article and Find Full Text PDFUnderstanding the cross-talk between mediators of infertility and COVID-19.
Reprod Biol
December 2021
Department of Zoology, Krishna Chandra College, Hetampur, West Bengal, India.
Article Synopsis
- COVID-19 is a global health crisis that not only affects breathing but also has significant impacts on the reproductive systems of both men and women.
- The study reviewed literature to examine the expression of SARS-CoV-2 entry factors in reproductive organs, finding that proteins like ACE-2 and TMPRSS2 are present in various reproductive tissues, which may lead to infertility issues.
- Additionally, the stress and mental health impacts of the pandemic are shown to negatively influence reproductive health, resulting in poor sperm quality for men and increased miscarriage risk for women.
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