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Poly ADP-ribosylation regulates Arc expression and promotes adaptive stress-coping.
Psychopharmacology (Berl)
January 2025
Department of Molecular Biology, Ariel University, Ariel, Israel.
Rationale: Rapid adaptation to stressful events is essential for survival and requires acute stress response and stress-coping strategy. However, the molecular mechanisms that govern this coping strategy have yet to be fully discovered.
Objectives: This study aims to investigate the effects of poly ADP-ribosylation (PARylation) on stress-coping strategies following acute stress and to identify the target genes influenced by Parp1-induced histone PARylation.
Exposure to warfare and demoralization: acute stress symptoms and disengaged coping as a mediators.
Eur J Psychotraumatol
December 2025
School of Social Work, Haifa, Israel.
Demoralization in the face of adversity is a common existential state. However, it has not been examined in reaction to warfare, and the mediators between the extent of exposure to war and demoralization in this context are also unknown. This study explored the associations of indirect exposure to war, acute stress symptoms, disengaged coping, and demoralization.
View Article and Find Full Text PDFBridging the Gap: The Importance of Non-technical Skills in Cardiology for Enhanced Patient Care and Team Performance.
Cureus
December 2024
Acute Medicine, Portsmouth Hospitals University NHS Trust, Portsmouth, GBR.
Cardiology, a high-acuity medical specialty, has traditionally emphasised technical expertise, often overshadowing the critical role of non-technical skills (NTS). This imbalance stems from the historical focus on procedural competence and clinical knowledge in cardiology training and practice, leaving a significant gap in the development of crucial interpersonal and cognitive abilities. However, emerging evidence highlights the significant impact of NTS on patient outcomes, team dynamics, and overall healthcare efficiency.
View Article and Find Full Text PDFCosts of Influenza Illness and Acute Respiratory Infections by Household Income Level: Catastrophic Health Expenditures and Implications for Health Equity.
Influenza Other Respir Viruses
January 2025
Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Background: Seasonal influenza illness and acute respiratory infections can impose a substantial economic burden in low- and middle-income countries (LMICs). We assessed the cost of influenza illness and acute respiratory infections across household income strata.
Methods: We conducted a secondary analysis of data from a prior systematic review of costs of influenza and other respiratory illnesses in LMICs and contacted authors to obtain data on cost of illness (COI) for laboratory-confirmed influenza-like illness and acute respiratory infection.
Identifying the most effective acute stress induction methods for producing SAM- and HPA-related physiological responses: a meta-analysis.
Anxiety Stress Coping
January 2025
Neuroendocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Background And Objectives: Laboratory-based stress inductions are commonly used to elicit acute stress but vary widely in their procedures and effectiveness. We compared the effects of stress induction techniques on measures of two major biological stress systems: the early sympathetic-adrenal-medullary (SAM) and the delayed hypothalamic-pituitary-adrenal (HPA) axis response.
Design: A review and meta-analysis to examine the relationship between stress induction techniques on cardiorespiratory and salivary measures of SAM and HPA system activity.
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