Case report: thyrotoxic periodic paralysis, an unusual cause of hypokalemia.

Acta Clin Belg

Department of Nephrology and Endocrinology, AZ Turnhout, Turnhout, Belgium.

Published: June 2024

AI Article Synopsis

  • Thyrotoxic periodic paralysis (TPP) is a rare condition linked to thyrotoxicosis, characterized by sudden muscle weakness due to low potassium levels.
  • A 19-year-old Thai male experienced acute weakness in his legs, which, along with severe hypokalemia and signs of hyperthyroidism, resulted in a TPP diagnosis caused by Graves' disease.
  • Doctors should be aware of TPP when patients show severe weakness, low potassium levels, and hyperthyroidism together.

Article Abstract

: Thyrotoxic periodic paralysis (TPP) is a type of hypokalemic periodic paralysis that is caused by an underlying thyrotoxicosis. It is a rare cause of hypokalemia due to intracellular potassium shift, causing acute muscle weakness.: We present a case of a 19-year-old male of Thai descent with acute proximal symmetric lower limb weakness. The combination of these symptoms with profound hypokalemia, rapid recovery after normalization of serum potassium, and evidence of hyperthyroidism led to the diagnosis of thyrotoxic periodic paralysis, in this case due to an underlying Graves' disease.: Clinicians should consider the diagnosis of TPP when a patient presents with the triad of acute paresis, profound hypokalemia and hyperthyroidism.

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Source
http://dx.doi.org/10.1080/17843286.2024.2365491DOI Listing

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