Mast cells: The Janus of type 2 inflammation. | LitMetric

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Mast cells: The Janus of type 2 inflammation. | LitMetric

Mast cells: The Janus of type 2 inflammation.

Johanna Kotrba Anne Dudeck

Immunity

Institute for Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany; Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany. Electronic address:

Published: June 2024

Mast cells (MCs) are effectors in type 2 immunity, well known for their detrimental roles in allergy. In this issue of Immunity, Alhallak et al. now identify a protective role of MCs against exacerbated immune responses mediated by prostaglandin E (PGE)-driven soluble ST2.

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.immuni.2024.05.011	DOI Listing

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