Aromatic bromination catalysed by 0.5-10 mol% of D-camphorsulfonic acid-BiCl3 with -bromosuccinimides (NBS) was carried out in MeCN under air conditions, and the procedure was extended to the reactions with -chlorosuccinimides (NCS) and -iodosuccinimides (NIS). The halogenation of some drugs and natural products was also attempted. One-pot bromination/Suzuki-Miyaura cross-coupling and bromination/Sonogashira coupling reactions were achieved without the removal of the solvent.
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