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Evidence Communication Rules for Policy (ECR-P) critical appraisal tool.
Syst Rev
January 2025
Statistical Laboratory, Department of Pure Mathematics and Mathematical Statistics, University of Cambridge, Cambridge, UK.
Background: Scientific papers increasingly put forward scientific-based policy recommendations (SPRs) as a means of closing the circle of science, policy and practice. Assessing the quality of such SPRs is crucial, especially within the context of a systematic review. Here, we present ECR-P (Evidence Communication Rules for Policy)-a critical appraisal tool that we have developed, which can be used in assessing not only the quality of SPRs but also the quality of their evidence base and how effectively these have both been communicated.
View Article and Find Full Text PDFCurrent status and perceived challenges of collaborative research in a leading pharmacy college in Iraq: a qualitative study.
BMC Med Educ
January 2025
Pharmaceutical Chemistry Department, College of Pharmacy, University of Baghdad, Baghdad, Iraq.
Background: Interdisciplinary collaboration among academic pharmacists is crucial for enhancing scientific research, discovering new drugs and modifying existing ones, besides solving pharmaceutical problems. This study aimed to explore the perception and experience of academic pharmacists regarding research collaboration.
Methods: A qualitative study through one-to-one face-to-face interviews with faculty members at the University of Baghdad/College of Pharmacy was conducted from May to July/2023.
The systemic evolutionary theory of the origin of cancer (SETOC): an update.
Mol Med
January 2025
Association for Systems Science, Via S. Stefano, 42, I-75100, Matera, Italy.
The Systemic Evolutionary Theory of the Origin of Cancer (SETOC) is a recently proposed theory founded on two primary principles: the cooperative and endosymbiotic process of cell evolution as described by Lynn Margulis, and the integration of complex systems operating in eukaryotic cells, which is a core concept in systems biology. The SETOC proposes that malignant transformation occurs when cells undergo a continuous adaptation process in response to long-term injuries, leading to tissue remodeling, chronic inflammation, fibrosis, and ultimately cancer. This process involves a maladaptive response, wherein the 'endosymbiotic contract' between the nuclear-cytoplasmic system (derived from the primordial archaeal cell) and the mitochondrial system (derived from the primordial α-proteobacterium) gradually breaks down.
View Article and Find Full Text PDFSocial Determinants, Mental Well-Being, and Disrupted Life Transitions Among Young Adults with Disabling Mental Health Conditions.
J Behav Health Serv Res
January 2025
Transitions to Adulthood Center for Research, Department of Psychiatry, UMass Chan Medical Schoo, 222 Maple Avenue, Shrewsbury, MA, 01545, USA.
This study sought to understand how young adults (age 18-25) with histories of mental health disorders are coping with disrupted transitions to adulthood during the COVID-19 pandemic. A cross-sectional web survey was conducted in March-June 2021 of 967 US young adults with pre-pandemic psychiatric disability to assess their current psychiatric status, interrupted transitions, and associations with social determinants including income, community participation, and social context. Mental health was assessed with the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7), and PTSD Checklist-Civilian Version.
View Article and Find Full Text PDFat 50: a data-driven history.
J Med Ethics
January 2025
Interdisciplinary Centre for Ethics, Jagiellonian University, Krakow, Poland.
In this paper, we take a data-driven approach to analyse intellectual trends over the first five decades of the (). Our data set, comprising all texts published in the since 1975, reveals not only the most distinctive topics of the in comparison to other key journals with similar profiles but also diachronic fluctuations in the prominence of certain topics. Overall, the distribution of topics shifted gradually, with each editorial period at the showing continuity with its immediate predecessor.
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