AI Article Synopsis

  • Clinical cancer registries aim to provide accurate data analysis and identify ways to enhance care in oncology, focusing on distinct cancer types.
  • A study of the Clinical Epidemiological Cancer Registry Brandenburg-Berlin from 2000 to 2018 revealed that squamous cell carcinoma (ESCC) was more prevalent than adenocarcinoma (EAC), although EAC cases are rising, especially among men.
  • Treatment primarily relied on chemotherapy and radiotherapy, with surgery rates at 19% for ESCC and 42% for EAC, raising concerns about the low surgical intervention despite the quality being comparable to international standards.

Article Abstract

Background: Clinical cancer registries are intended to reflect the reality of care through differentiated data analysis and, if necessary, to offer approaches for improving care.

Methods: For the years 2000-2018, the data of the Clinical Epidemiological Cancer Registry Brandenburg-Berlin were examined separately for adenocarcinoma and squamous cell carcinoma with respect to epidemiology and health care reality.

Results: Between 2000 and 2018 a total of 3207 esophageal cancers were documented in the cancer registry, of which 2182 were squamous cell carcinomas (ESCC), 843 adenocarcinomas (EAC) and 182 various others or missing histology. During the observation period there was a clear dominance of ESCC but with a significant increase in EAC in both sexes. Overall, the rate of new cases was 5 times higher for men than for women. The relative 5‑year survival probability of all esophageal cancers was 17.4% in men and 22.5% in women. Patients with EAC survived significantly longer than those with ESCC. Radiotherapy and chemotherapy, individually or in combination, were mainly used as treatment methods. Surgery was performed on 19% of ESCC and 42% of EAC.

Conclusion: The proportion of ESCC in Brandenburg is still significantly higher than EAC, with a significant increase for the latter, especially in men. Although locally advanced tumors have been significantly more common, modern neoadjuvant concepts have rarely been documented, and although the quality of the surgery is comparable to the international standard, surgery is carried out in relatively few patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413088PMC
http://dx.doi.org/10.1007/s00104-024-02110-0DOI Listing

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