This paper proposes an optimization method aimed at addressing the challenge of balancing system imaging performance and tolerance performance. The method is based on the high-order nodal aberration theory. The calculation method for high-order aberration coefficients is derived, along with the change in aberrations after introducing tolerance perturbation. The evaluation system includes both the imaging performance of the system and its tolerance factors. A comprehensive merit function is created for optimization. Three aspherical system examples were designed for verification, and the optimization results of this method show significantly lower tolerance sensitivity compared to the general optimization results and the SAB function optimization results of CODE V.
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http://dx.doi.org/10.1364/OE.517510 | DOI Listing |
Mater Horiz
January 2025
Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu 610031, China.
Flexible hydrogel sensors have found extensive applications. However, the insufficient sensing sensitivity and the propensity to freeze at low temperatures restrict their use, particularly in frigid conditions. Herein, a multifunctional eutectogel with high transparency, anti-freezing, anti-swelling, adhesive, and self-healing properties is prepared by a one-step photopolymerization of acrylic acid and lauryl methacrylate in a binary solvent comprising water and deep eutectic solvent (DES).
View Article and Find Full Text PDFCardiovasc Diabetol
January 2025
Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Background: Diabetic myocardial disorder (DbMD, evidenced by abnormal echocardiography or cardiac biomarkers) is a form of stage B heart failure (SBHF) at high risk for progression to overt HF. SBHF is defined by abnormal LV morphology and function and/or abnormal cardiac biomarker concentrations.
Objective: To compare the evolution of four DbMD groups based on biomarkers alone, systolic and diastolic dysfunction alone, or their combination.
Anesthesiology
January 2025
Takeda Development Center Americas, Inc., Lexington, MA, USA.
Background: Orexin neuropeptides help regulate sleep/wake states, respiration, and pain. However, their potential role in regulating breathing, particularly in perioperative settings, is not well understood. TAK-925 (danavorexton), a novel, orexin receptor 2-selective agonist, directly activates neurons associated with respiratory control in the brain and improves respiratory parameters in rodents undergoing fentanyl-induced sedation.
View Article and Find Full Text PDFEcol Evol
January 2025
Minderoo Foundation Perth Western Australia Australia.
Coral reefs worldwide are threatened by increasing ocean temperatures because of the sensitivity of the coral-algal symbiosis to thermal stress. Reef-building corals form symbiotic relationships with dinoflagellates (family Symbiodiniaceae), including those species which acquire their initial symbiont complement predominately from their parents. Changes in the composition of symbiont communities, through the mechanisms of symbiont shuffling or switching, can modulate the host's thermal limits.
View Article and Find Full Text PDFCureus
December 2024
Department of Cardiovascular Medicine, Faculty of Medicine, Tottori University, Yonago, JPN.
The purpose of this study is to examine the pregestational BMI value that results in insulin use in Japanese patients with gestational diabetes mellitus (GDM) and to assess whether the type of GDM treatment affects postpartum glucose tolerance. This retrospective study included 21 GDM patients treated until parturition at our department from 2013 to 2017. We calculated the pregestational BMI related to insulin treatment and the significant elevation in homeostasis model assessment of insulin resistance (HOMA-IR) by receiver operating characteristics curve (ROC) analysis.
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