AI Article Synopsis
- The article discusses the diagnosis and treatment of hepatitis B virus (HBV) infection in children, emphasizing recent advancements in antiviral treatments for chronic hepatitis B (CHB).
- It highlights key clinical issues, such as choosing the right antiviral regimen for children in different phases of HBV infection and determining when treatment should start, especially for infants.
- The article also incorporates new guidelines from Chinese experts to offer practical recommendations for healthcare providers dealing with pediatric CHB cases.
Article Abstract
Diagnosis and treatment of hepatitis B virus (HBV) infection in children is a hotspot of concern in the field of HBV infection. This article reviews the current status and progress of antiviral treatment for children with chronic hepatitis B (CHB) in recent years, focusing on clinical issues such as the choice of antiviral treatment regimen for children with HBeAg-positive CHB (immune-clearance phase), the necessity of antiviral treatment for children with HBeAg-positive HBV infection (immune-tolerance phase), and the timing of antiviral treatment for infants with HBV infection, to explore the relevant factors that may affect the clinical cure of children with CHB. At the same time, based on the expert consensus on the prevention and treatment of children with CHB just published by Chinese experts, relevant diagnosis and treatment plans are proposed, with a view to providing reference and basis for clinical decision-making in children with CHB.
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| http://dx.doi.org/10.3760/cma.j.cn501113-20240408-00181 | DOI Listing |
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