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Comparative Analysis of the Postoperative Analgesic Effect of Caudal Ropivacaine Versus Ropivacaine With Nalbuphine in Infra-Umbilical Pediatric Surgeries: A Randomized, Double-Blind Pilot Study.
Cureus
December 2024
Pediatric Surgery, All India Institute of Medical Sciences, Raipur, Raipur, IND.
Postoperative pain in children leads to an immense stress response than adults, leading to an increased hospital stay and "pain memory." Caudal epidural anesthesia is one of the most reliable, popular, and safe techniques that provide proper analgesia for infra-umbilical surgeries. A combination of local anesthetics and opioids reduces the dose-related adverse effects of each drug independently.
View Article and Find Full Text PDFBackground: Uncertainty about optimal tranexamic acid (TXA) dosage has led to significant practice variation in hip arthroplasty. We aimed to identify the optimal i.v.
View Article and Find Full Text PDFEffect of different doses of dexmedetomidine on atrial fibrillation in adults after cardiac surgery.
J Cardiovasc Pharmacol
January 2025
Department of Anesthesiology, Jining No. 1 People's Hospital, Jining, Shandong, China.
In this study, we compared the effects of various doses of dexmedetomidine on the incidence of atrial fibrillation following cardiac surgery in adults. 224 adult patients who underwent elective cardiac surgery were randomly assigned to two groups. The DEX0.
View Article and Find Full Text PDFSex Differences in Neurological Outcome at 6 and 12 Months Following Severe Traumatic Brain Injury. An Observational Analysis of the OXY-TC Trial.
J Neurotrauma
January 2025
Department of Anaesthesia and Intensive Care, Centre Hospitalier Universitaire Grenoble, and Inserm, U1216, Grenoble Institut Neurosciences, University Grenoble Alpes, Grenoble, France.
The effect of sex in outcomes after severe traumatic brain injury (TBI) remains uncertain. We explored whether outcomes differed between women and men after standardized care management during the first 5 days in the intensive care unit (ICU). This study was an observational analysis of the OXY-TC multicenter randomized clinical trial between June 15, 2016 and April 17, 2021.
View Article and Find Full Text PDFUtility of large V-Y advancement of the latissimus dorsi myocutaneous flap in the reconstruction of large thoracic defects: a case series and literature review.
JPRAS Open
March 2025
Sir Charles Gairdner Hospital, Nedlands, Perth, Western Australia, 6009.
Background: Trunk reconstruction following sarcoma excision involves significant defects. Pedicled and free latissimus dorsi myocutaneous flap (LDMF) reconstruction is commonly employed for thoracic defects; however, skin paddle design is limited to 10-12 cm to achieve primary donor closure. Paucity of data exists regarding the utility of V-Y advancement of LDMF, previously described for moderately sized thoracic defects.
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