The feature issue of titled "Advances in Optical Biosensors for Biomedical Applications" presents a comprehensive collection of cutting-edge optical biosensor research. With the growing demand for sensitive, label-free, and real-time detection of biological analytes, optical biosensors have emerged as important devices in a wide range of biomedical applications, including medical diagnostics, bioanalysis, and personalised healthcare. This collection of 26 papers highlights recent advances and innovations in the development, design, and implementation of optical biosensors. The feature issue serves as an opportunity for disseminating ground-breaking findings, promoting new ideas, and inspiring further developments in optical biosensors for medical applications. The authors provide breakthrough technology, innovative approaches, and practical clinical applications that have the potential to revolutionize healthcare and biomedical research.
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http://dx.doi.org/10.1364/BOE.527613 | DOI Listing |
Appl Biochem Biotechnol
January 2025
Ethnopharmacology and Algal Biotechnology Laboratory, Department of Botany, School of Life Sciences, Periyar University, Salem, Tamil Nadu, 636011, India.
In this present investigation, plant-mediated synthesis of titanium oxide (TiO) nanoparticles was synthesized from seagrass (Thalassia hemprichi) using the hot plate combustion method (HPCM). Synthesized TiO nanoparticles optical, functional, structural, and morphology properties were analyzed by UV-visible spectroscopy, Fourier transform infrared spectroscopy (FT-IR), powder X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). SEM analysis confirmed the spherical shape of the TiO nanoparticles were observed in various sizes, viz.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Background: Tau aggregates, a hallmark of Alzheimer's disease (AD) and other tauopathies, spread throughout the brain, contributing to neurodegeneration. How this propagation occurs remains elusive. Previous research suggests that tau-seed interactors play a crucial role.
View Article and Find Full Text PDFEur J Dent
December 2024
Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha, Qatar, College of Dental Medicine, Qatar University, Doha, Qatar.
Advances in the field of nanomaterials are laying the foundation for the fabrication of nanosensors that are sensitive, selective, specific, cost-effective, biocompatible, and versatile. Being highly sensitive and selective, nanosensors are crucial in detecting small quantities of analytes and early diagnosis of diseases. These devices, operating on the nanoscale, detect signals, such as physical, chemical, optical, electrochemical, or biological, and then transduce them into a readable form.
View Article and Find Full Text PDFTypical biosensing platforms are based on the "lock-and-key" approach, providing high specificity and sensitivity for environmental and food safety monitoring. However, they are limited in their ability to detect multiple analytes simultaneously. With the use of pattern identification methods, biosensor arrays can detect faint fluctuations caused by multiple analytes with similar properties in complex systems.
View Article and Find Full Text PDFLangmuir
January 2025
Department of Chemistry and Centre for Advanced Studies in Chemistry, Panjab University, Chandigarh 160014, India.
Herein, we present a novel liquid crystal (LC)-based sensing platform utilizing microgel-stabilized Pickering LC droplets dispersed in water for simple and label-free detection of proteins in an aqueous environment. This could be achieved by tailoring the surface of 4-cyano-4'-pentylbiphenyl (5CB) LC droplets dispersed in aqueous medium through the interfacial adsorption of poly(-isopropylacrylamide) (PNIPAM) microgel particles, followed by the introduction of model surfactants, such as anionic sodium dodecyl sulfate and cationic dodecyltrimethylammonium bromide. These surfactant/microgel complex-coated LC droplets underwent a configurational transition from radial-to-bipolar under a polarized optical microscope, upon exposure to model proteins, namely bovine serum albumin and lysozyme.
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