[This corrects the article DOI: 10.7759/cureus.61795.].

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Aims: The Tpeak-Tend interval on electrocardiogram may be a predictor of worse outcomes in Takotsubo syndrome (TTS), but the mechanisms have not been fully determined. This study aimed to investigate the relationships between the corrected Tpeak-Tend (cTp-e) interval and coronary microvascular-dysfunction (CMD) assessed by the angiography-derived index of microvascular resistance (Angio-IMR) and the in-hospital prognosis in patients with TTS.

Methods And Results: We retrospectively evaluated 111 consecutive patients admitted for TTS who underwent coronary angiography at Kindai University Hospital from October 2009 to July 2023.

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Prevalence and severity of QT prolongation and other ECG abnormalities in takotsubo syndrome.

J Electrocardiol

January 2025

Department of Cardiology, Morriston Regional Cardiac Centre, Morriston Hospital, Heol Maes Eglwys, Swansea SA6 6NL, UK.

Article Synopsis
  • The study investigates the occurrence of long QT interval (LQT) in patients with takotsubo syndrome (TS), revealing a significant increase in LQT prevalence 24-48 hours after symptoms start, with many cases being severe.
  • A total of 58 female patients were analyzed, with common symptoms such as chest pain and various ECG abnormalities, including T-wave inversion and ST segment changes, noted after symptom onset.
  • The findings suggest that monitoring should continue for at least 96 hours post-symptom onset to ensure that the QT interval normalizes, particularly since many patients do not show normal ECGs early on.
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Background: Extensive myocardial edema is a key feature of acute takotsubo syndrome (TTS) and it can be quantitatively assessed by T2 mapping cardiac magnetic resonance (CMR) imaging. Clinical correlates of myocardial edema in TTS are not well characterized.

Methods: Sixty patients with acute TTS underwent CMR with T2 mapping within one week of hospitalization.

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Takotsubo syndrome induced by severe hyponatraemia in mineralocorticoid-responsive hyponatraemia of the elderly: a case report.

Eur Heart J Case Rep

October 2024

Division of Cardiology, Department of Internal Medicine, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-ku, Yokohama, Kanagawa 227-8501, Japan.

Article Synopsis
  • An 85-year-old woman's severe hyponatraemia (low sodium levels) led to transient loss of consciousness and subsequent cardiac dysfunction, ultimately diagnosed as Takotsubo syndrome, indicating a heart condition triggered by stress.
  • The patient was treated with hypertonic saline to gradually correct her low sodium levels, which required careful monitoring to avoid complications, and her condition improved over 14 days.
  • This case highlights the importance of promptly treating severe hyponatraemia in elderly patients, raises concerns about current treatment protocols for mineralocorticoid-responsive hyponatraemia (MRHE), and suggests a possible link between MRHE and acute cardiomyopathy.
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