AI Article Synopsis

  • * Patients may experience various types of nerve damage, including mononeuropathy and polyneuropathy, highlighting the need to consider leprosy when diagnosing peripheral neuropathy.
  • * The paper outlines three case studies, detailing the clinical features, diagnostic methods, and treatment strategies for leprosy-related nerve involvement.

Article Abstract

Leprosy, caused by the complex, manifests as a chronic infection. Its hallmark presentation involves the neurocutaneous syndrome, characterized by peripheral nerve involvement and dermatologic lesions. Neurological complications significantly contribute to disability in leprosy patients. Peripheral neuropathy may manifest acutely or chronically, in either axonal or demyelinating forms, and can present as mononeuropathy, mononeuropathy multiplex, or polyneuropathy. The diverse clinical presentations emphasize the importance of considering leprosy in the differential diagnosis of peripheral neuropathy, enabling appropriate investigative approaches. Skin and nerve biopsies, slit skin smears, and nerve conduction studies serve as crucial diagnostic tools for identifying peripheral nerve involvement in leprosy. In this paper, we present three cases of leprosy with peripheral nerve involvement, discussing their clinical spectrum, diagnostic approach, and management.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11159591PMC
http://dx.doi.org/10.7759/cureus.59884DOI Listing

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