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Maternal-fetal dyad beyond the phenomenology of pregnancy: from primordial cardiovascular prevention on out, do not miss this boat! | LitMetric

AI Article Synopsis

  • Pregnancy is a significant challenge for a woman's heart and blood system, and having pre-existing heart issues or metabolic problems can lead to bad outcomes during pregnancy and increase the risk of heart diseases later on.
  • The health environment provided by the mother can impact the cardiovascular well-being of the child, as factors during pregnancy can affect the child's growth and future heart health.
  • This review discusses the latest insights on how both mothers and their unborn children influence cardiovascular health, emphasizing prevention strategies throughout different stages of life.

Article Abstract

Pregnancy represents a stress test for every woman's cardiovascular (CV) system, and a pre-existing maternal unfavorable cardio-metabolic phenotype can uncover both adverse pregnancy outcomes and the subsequent development of cardiovascular disease (CVD) risk factors during and after pregnancy. Moreover, the maternal cardiac and extracardiac environment can affect offspring's cardiovascular health through a complex mechanism called developmental programming, in which fetal growth can be influenced by maternal conditions. This interaction continues later in life, as adverse developmental programming, along with lifestyle risk factors and genetic predisposition, can exacerbate and accelerate the development of CV risk factors and CVD in childhood and adolescence. The aim of this narrative review is to summarize the latest evidences regarding maternal-fetal dyad and its role on primordial, primary and secondary CV prevention.

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Source
http://dx.doi.org/10.1016/j.cpcardiol.2024.102695DOI Listing

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