Reproducibility and air gap pockets of 3D-printed brachytherapy applicator placement in high-dose-rate skin cancer.

Phys Med

The National Institute of Medicine of the Ministry of the Interior and Administration, Woloska 137, 02-507, Warsaw, Poland; Department of Dermatology, Centre of Postgraduate Medical Education, 02-507 Warsaw, Poland.

Published: July 2024

AI Article Synopsis

  • This study explores the use of 3D-printed brachytherapy applicators for precise skin cancer treatment, focusing on applicator placement accuracy and reducing air gaps.
  • A cohort of 20 skin cancer patients received high dose rate (HDR) brachytherapy using custom-made applicators based on CT scans, showcasing a placement error of less than 1.0 mm on average.
  • The findings confirm that personalized 3D-printed applicators enhance treatment precision, potentially improving patient outcomes by minimizing radiation exposure to healthy tissue.

Article Abstract

Background And Purpose: This study aimed to investigate the reproducibility of a novel approach using 3D printed brachytherapy applicators for the treatment of skin cancer. Specifically, we aimed to assess the accuracy of applicator placement and to minimize the existence of air gap pockets between the applicator and the patient's skin.

Materials And Methods: A total of 20 patients plans diagnosed with skin cancer were enrolled in this study. All patients underwent high dose rate (HDR) brachytherapy. To ensure precise applicator placement, patient-specific 3D printed applicators were designed based on individual body and tumor topography, utilizing data obtained from computer tomography (CT) scans. All applicators were fabricated using fused deposition modeling technology.

Results: The error in applicator placement was measured and found to be less than 1.0 mm on average, with a standard deviation of 0.9 mm. Additionally, the average error in air gap pockets between the applicator and the patient's skin was 0.4 mm (standard deviation was 0.5 mm). The study demonstrated that the personalized approach of 3D printed brachytherapy applicator placement in skin cancer treatment yielded highly accurate results. The average error of less than 1.0 mm in applicator positioning and the minimal air gap pockets demonstrated the reproducibility and precision of this technique.

Conclusion: Our study establishes the reproducibility and accuracy of 3D-printed brachytherapy applicator placement in the treatment of skin cancer. This personalized treatment approach offers a highly precise method for delivering radiation therapy, minimizing the risk to adjacent healthy tissues, and enhancing overall patient outcomes.

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Source
http://dx.doi.org/10.1016/j.ejmp.2024.103401DOI Listing

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