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Nanostructures in Orthopedics: Advancing Diagnostics, Targeted Therapies, and Tissue Regeneration.
Materials (Basel)
December 2024
Department of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences (WULS-SGGW), 02-787 Warsaw, Poland.
Nanotechnology, delving into the realm of nanometric structures, stands as a transformative force in orthopedics, reshaping diagnostics, and numerous regenerative interventions. Commencing with diagnostics, this scientific discipline empowers accurate analyses of various diseases and implant stability, heralding an era of unparalleled precision. Acting as carriers for medications, nanomaterials introduce novel therapeutic possibilities, propelling the field towards more targeted and effective treatments.
View Article and Find Full Text PDFβ-adrenergic receptor-induced E-S potentiation in the dorsal and ventral hippocampus.
Front Synaptic Neurosci
December 2024
Laboratory of Physiology, Department of Medicine, University of Patras, Patras, Greece.
β-adrenergic receptors (β-ARs) play a critical role in modulating learning, memory, emotionality, and long-term synaptic plasticity. Recent studies indicate that β-ARs are necessary for long-term potentiation (LTP) induction in the ventral hippocampus under moderate synaptic activation conditions that do not typically induce LTP. To explore potential dorsoventral differences in β-AR-mediated effects, we applied the β-AR agonist isoproterenol (10 μM, 30 min) to dorsal and ventral hippocampal slices, recording field excitatory postsynaptic potentials (fEPSPs) and population spikes (PSs) from the CA1 region.
View Article and Find Full Text PDFVolumetric Additive Manufacturing for Cell Printing: Bridging Industry Adaptation and Regulatory Frontiers.
ACS Biomater Sci Eng
January 2025
Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Manipal, 576104 Karnataka, India.
Volumetric additive manufacturing (VAM) is revolutionizing the field of cell printing by enabling the rapid creation of complex three-dimensional cellular structures that mimic natural tissues. This paper explores the advantages and limitations of various VAM techniques, such as holographic lithography, digital light processing, and volumetric projection, while addressing their suitability across diverse industrial applications. Despite the significant potential of VAM, challenges related to regulatory compliance and scalability persist, particularly in the context of bioprinted tissues.
View Article and Find Full Text PDFImmunological characterization of pleural effusions in pediatric patients.
Front Immunol
December 2024
Department of General Pediatrics and Neonatology, Saarland University, Campus Homburg, Homburg, Germany.
Background: The pleural cavity represents a unique immunological compartment that can mount inflammatory reactions during infections, after surgery and in chronic immunological diseases. The connection between systemic immune reactions in the blood and local immune reactions in pleural effusions remains unclear. This study provides the first comprehensive immunological characterization of paired blood and pleural effusion samples, utilizing combined cell and cytokine analyses in pediatric patients undergoing cardiac surgery.
View Article and Find Full Text PDFAI frontiers in emergency care: the next evolution of nursing interventions.
Front Public Health
December 2024
Medical Surgical Department, College of Nursing, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
This scoping review explores the utilization of artificial intelligence in emergency nursing, assessing its impact, potential benefits, and the obstacles faced in its adoption. It covers the scope of AI from advanced triage protocols to continuous monitoring of patients, assistance in diagnosis, and providing support for clinical decisions. The review notes that AI in emergency healthcare can lead to more efficient care and timely, data-driven actions, but also highlights significant issues such as safeguarding patient data, the necessity for dependable infrastructure, and concerns over discriminatory algorithms.
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