Subacute bacterial endocarditis (SBE) evolves over weeks to months, often without typical features of acute endocarditis. Its presentation progresses gradually until possibly complicated by sentinel events, such as a cerebrovascular accident from embolization or a ruptured vessel. This is a case of SBE presenting as symptomatic anemia in a female patient with severe aortic regurgitation (AR) and mitral regurgitation (MR) due to bi-valvular vegetations in the absence of typical acute endocarditis and congestive heart failure (CHF) features.
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http://dx.doi.org/10.7759/cureus.59771 | DOI Listing |
Viruses
January 2025
Service des Maladies Infectieuses et Tropicales, Hôpital Pitié Salpêtrière, APHP Sorbonne Université, 75013 Paris, France.
Phage therapy is experiencing renewed interest, particularly for antibiotic-resistant infections, and may also be useful for difficult-to-treat cases where surgery to remove foreign infected material is deemed too risky. We report a case of recurrent endocarditis with Bentall infection treated successfully with a combination of antibiotics and phages.
View Article and Find Full Text PDFPathogens
December 2024
Intensive Care Unit, Department of Anesthesiology and Critical Care, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Ventriculo-meningitis or nosocomial meningitis/ventriculitis is a severe nosocomial infection that is associated with devastating neurological sequelae. The cerebrospinal fluid isolates associated with the infection can be Gram-positive or -negative, while the spp. is rarely identified.
View Article and Find Full Text PDFMedicina (Kaunas)
January 2025
Department of Infectious Diseases, "St. Parascheva" Clinical Hospital of Infectious Diseases, 700116 Iasi, Romania.
: Infective endocarditis (IE) is a severe, life-threatening infection of the endocardial surface. Its incidence has shifted towards older, immunocompromised patients and those with cardiac devices. : This study was conducted at the "Sf.
View Article and Find Full Text PDFAntibiotics (Basel)
January 2025
Division of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.
: is a leading cause of infective endocarditis (IE), which causes diverse clinical symptoms and even death. Recurrence after treatment is a crucial problem in IE, possibly caused by the presence of "persister" cells, a small bacterial population that can survive antimicrobials. In this study, the residual risk for penicillin G (PCG) and gentamicin (GM), used for treating IE, to induce persisters, was investigated.
View Article and Find Full Text PDFBiomedicines
January 2025
Laboratory of Genome Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 650002 Kemerovo, Russia.
Infective endocarditis (IE) is an infectious disease caused by the hematogenous dissemination of bacteria into heart valves. Improving the identification of pathogens that cause IE is important to increase the effectiveness of its therapy and reduce the mortality caused by this pathology. Ten native heart valves obtained from IE patients undergoing heart valve replacements were analyzed.
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