Detection of Steroids in Topical Fairness Preparations Using Histamine Wheal Test.

Indian Dermatol Online J

Department of Dermatology, Ranga's Centre of Dermatology, Coimbatore, Tamil Nadu, India.

Published: February 2024

Topical corticosteroid (TC) abuse is a common, worldwide, problem. One of the recent emerging concerns is the adulteration of TC in fairness cream. The presence of TC in skin-whitening cosmetic creams can be detected by high-performance liquid chromatography (HPLC). Since HPLC is expensive, time-taking and not easily available, we suggest the use of histamine wheal test as a simple and inexpensive test to detect the presence of topical steroids in fairness cream.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152470PMC
http://dx.doi.org/10.4103/idoj.idoj_321_23DOI Listing

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