HOW I DO IT: Cushing's disease-selective adenomectomy via an endoscopic transsphenoidal approach.

Acta Neurochir (Wien)

Leeds General Infirmary, Leeds, UK.

Published: June 2024

Background: An ACTH-secreting pituitary adenoma is the most common cause of excessive endogenous glucocorticoid production resulting in Cushing's Syndrome. A multidisciplinary approach is paramount. Selective adenomectomy is the treatment of choice.

Method: Endoscopic transnasal transsphenoidal approach to the tumour, along with techniques for resection, are demonstrated.

Conclusion: Endoscopic transsphenoidal approaches with its magnified view of the pituitary gland allows precise microsurgical dissection during selective adenomectomy. This technique increases the possibility of proving a gross total resection, leading to clinical and biochemical cure in these patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156730PMC
http://dx.doi.org/10.1007/s00701-024-06078-yDOI Listing

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