Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/17460441.2024.2364637 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Understanding the complexity of near-infrared quantification of highly porous patient-tailored drug products by utilizing chemometrics and stimulated Raman imaging.
Int J Pharm
January 2025
Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen 2100 Copenhagen, Denmark. Electronic address:
Additively manufactured drug products, typically produced using small-scale, on-demand batch mode, require rapid and non-destructive quantification methods. A tunable modular design (TMD) approach combining porous polymeric freeze-dried modules and an additive manufacturing method, inkjet printing, was proposed in an earlier study to fabricate accurate and patient-tailored doses of an antidepressant citalopram hydrobromide. This approach addresses the unmet medical needs associated with antidepressant tapering.
View Article and Find Full Text PDFAll-in-one microfluidic immunosensing device for rapid and end-to-end determination of salivary biomarkers of cardiovascular diseases.
Biosens Bioelectron
March 2025
School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang, 315200, China. Electronic address:
Routine screening for cardiovascular diseases (CVDs) through point-of-care assays for at-home or community-based testing of salivary biomarkers can significantly improve patient outcomes. However, its translatability has been hindered by a dearth of biosensing devices that streamline assay procedures for rapid biomarker quantitation. To address this challenge through end-to-end engineering, we developed an in-house, all-in-one microfluidic immunosensing device that integrates on-chip vibration-enhanced incubation, magnetic-assisted separation using immune magnetic bead probes, and colorimetric readout via absorbance measurements.
View Article and Find Full Text PDFDNA Nanolock-Based Logic Gate-Directed Reciprocal Feedback for Stepwise Cell Typing and Combination Treatment.
Anal Chem
December 2024
Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE; College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.
Article Synopsis
- There's a critical need for monitoring multiple biomarkers in living cells for accurate disease diagnosis and early intervention.
- A modular DNA logic gate nanomachine is introduced, which uses G-quadruplex-locked gold nanocages to identify cells and deliver drugs through a series of simple logic operations.
- This system effectively processes input from disease biomarkers to produce fluorescence signals, enabling precise cell identification and controlled treatments, expanding the potential of biocomputing in medical applications.
Toward precision medicine: End-to-end design and construction of integrated microneedle-based theranostic systems.
J Control Release
January 2025
Institute of Burn Research, State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University, Chongqing 400038, China. Electronic address:
With the growing demand for precision medicine and advancements in microneedle technology, microneedle-based drug delivery systems have evolved into integrated theranostic platforms. However, the development of these systems is currently limited by the absence of clear conclusions and standardized construction strategies. The end-to-end concept offers an innovative approach to theranostic systems by creating a seamless process that integrates target sampling, sensing, analysis, and on-demand drug delivery.
View Article and Find Full Text PDFLight-assisted carbon dioxide reduction in an automated photoreactor system coupled to carbonylation chemistry.
Chem Sci
December 2024
Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), Universiteit van Amsterdam (UvA) 1098 XH Amsterdam The Netherlands
Continuous-flow methodologies offer promising avenues for sustainable processing due to their precise process control, scalability, and efficient heat and mass transfer. The small dimensions of continuous-flow reactors render them highly suitable for light-assisted reactions, as can be encountered in carbon dioxide hydrogenations. In this study, we present a reactor system emphasizing reproducibility, modularity, and automation, facilitating streamlined screening of conditions and catalysts for these processes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!