The synthesis of deuterated -difluoroalkenes selective deuterodefluorination of β-CF-cinnamates using a nickel catalyst has been reported for the first time. Commercially available deuterated formic acid is a cheap and convenient deuterium source. The nickel-catalyst showed high selectivity for monodefluorination and avoided competitive reactions such as multiple defluorination or hydrogenation.
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| http://dx.doi.org/10.1039/d4cc00918e | DOI Listing |
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