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The Association of Leser-Trélat Sign with Cutaneous Undifferentiated Pleomorphic Sarcoma.
Indian J Dermatol
October 2024
From the Department of Dermatology, Mohammed the VIth University Hospital, Medical School of Oujda, Mohammed First University, Oujda, Morocco E-mail:
Skin as a Reflection of Gut Health: An Overview of Dermatological Manifestations in Primary Neoplastic and Autoimmune Gastrointestinal Disorders.
Cureus
October 2024
Internal Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Gastrointestinal (GI) diseases can present with several extraintestinal manifestations, and cutaneous signs and symptoms are most frequent. Although conventionally GI and skin are considered two entirely separate organ systems, they are closely correlated in origin. An increasing amount of data highlights the complex relationship between GI and dermatological conditions.
View Article and Find Full Text PDFSign of Leser-Trélat Associated with Kaposi Sar-coma in an Immunocompetent Man.
Skinmed
August 2024
Department of Dermatology, Rowan University School of Osteopathic Medicine, Stratford, NJ.
Article Synopsis
- * A punch biopsy confirmed the presence of Kaposi sarcoma (KS), with immunohistochemistry showing positive results for human herpesvirus 8 (HHV8).
- * He was referred to oncology for management, found to be immunocompetent, and had a negative HIV test, with CT scans showing no internal organ involvement.
Leser-Trelat sign in a man with breast cancer.
Indian J Dermatol Venereol Leprol
April 2024
Department of Dermatology, Venereology & Leprosy, Government Medical College Srinagar, India.
Variability of Leser-Trélat Sign Secondary to Melanoma In Situ.
Cureus
February 2024
Family Medicine, Carilion Clinic, Roanoke, USA.
Article Synopsis
- The Leser-Trélat sign (LTS) is linked to melanoma and is typically seen as an abrupt appearance of multiple seborrheic keratoses, but this case shows a more subtle presentation.
- A 64-year-old woman with no prior skin cancer history developed new SKs along with a concerning macular nevus, which led to a diagnosis of melanoma in situ after a biopsy.
- This case underlines the need for careful observation of unusual skin changes, as subtle signs can indicate serious underlying conditions like melanoma.
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