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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152780 | PMC |
http://dx.doi.org/10.1097/CLD.0000000000000217 | DOI Listing |
Int J Nanomedicine
December 2024
Department of Dermatology, Affiliated Hospital of Shandong Second Medical University, School of Clinical Medicine, Shandong Second Medical University, Weifang, 261031, People's Republic of China.
Background: Melanoma is an aggressive skin tumor with limited therapeutic options due to rapid proliferation, early metastasis, and poor prognosis. Baicalin (BA), a natural flavonoid, shows promise in inducing ferroptosis and apoptosis but faces challenges of poor solubility and bioavailability. To address these issues, we developed a multifunctional drug delivery system: manganese-doped ZIF-8 nanoparticles (ZIF(Mn)) loaded with BA and modified with folic acid (FA) and polyethylene glycol (PEG).
View Article and Find Full Text PDFFood Sci Nutr
December 2024
Department of Pathobiology, Faculty of Veterinary Medicine Bu-Ali Sina University Hamedan Iran.
In this study, chitosan (C)-polyvinyl alcohol (P) edible film containing bio-fabricated nanosilver particles (nAg) (as antimicrobial agent) and beetroot peel extract (BRPE) (as antioxidant agent and pH indicator) was used as spoilage indicator in cold-stored rainbow trout fillets. DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity (43.02%), reducing power (2.
View Article and Find Full Text PDFFood Sci Nutr
December 2024
Department of Information, College of Medicine and Biological Information Engineering Northeastern University Shenyang China.
This study investigated the effects of varying concentrations of peanut shell flavonoids (PSFs) on the properties of peanut meal extract-tilapia skin protein composite films and their impact on cherry tomatoes preservation. Peanut meal alcohol extract (Pe) and tilapia skin protein (Co) were used as base materials, combined with PSFs to prepare composite films with excellent antioxidant properties. The results demonstrated that the optimized composite films exhibited superior mechanical properties, with a tensile strength of 9.
View Article and Find Full Text PDFFood Sci Nutr
December 2024
Department of Biochemistry and Biotechnology, School of Health Sciences University of Thessaly Larissa Greece.
Previous studies have shown that seaweed extracts (HMEs) possess antioxidant properties, but the molecular mechanisms accounting for this activity are not known. Thus, the present study investigated the molecular mechanisms through which HME exerted its antioxidant activity in human mesenchymal stem cells (WJ-MSCs). After the isolation of HME, its chemical composition was analyzed with gas chromatography mass spectrometry, indicating that it contained amino acids, organic acids, organic amides, sugar alcohols, saturated fatty acids, hydrogenated diterpene alcohols, and other organic compounds.
View Article and Find Full Text PDFFood Sci Nutr
December 2024
Department of Pharmacology, School of Pharmacy Xinjiang Medical University Urumqi Xinjiang China.
Rupr. is a berry fruit shrub found in the north-western region of China, locally its fruit is consumed as a tea ingredient a part of the daily diet, for treatment of different diseases like eczema, and for cardiovascular care as a traditional remedy. In the current study, an optimized ultrasound-assisted extraction (UAE) method is developed using response surface methodology (RSM) to extract anthocyanins from the fruit.
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