Patterned hair loss (PHL) is a severe hair condition that affects both sexes. Mesotherapy is a treatment that involves microinjecting medications and/or vitamins into the middle layer of the skin. Mesotherapy reduces systemic adverse effects by delivering drugs directly to the hair follicle, increasing local bioavailability while lowering systemic exposure. Local side effects and reactions may develop due to mesotherapy. This study systematically evaluated the safety and efficacy of mesotherapy to minoxidil 5%, as well as addressing its limitations, dosing, and technique, with the intent of providing valuable trials and insights for clinicians and patients considering mesotherapy for improved androgenetic alopecia (AGA) outcomes. The literature search carried out by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria yielded 11 relevant studies from an initial pool of 18 articles. These studies covered various aspects of the role of mesotherapy and minoxidil in AGA, including techniques, complications, limitations, and outcomes. In conclusion, available trials and research on mesotherapy and minoxidil demonstrated excellent statistical significance and a high patient satisfaction rate, with the exception of two publications that took into account certain uncommon adverse effects of mesotherapy. However, recent research suggests that a mesotherapy method for alopecia with a low risk of side effects is effective.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152360 | PMC |
| http://dx.doi.org/10.7759/cureus.59705 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A bibliometric analysis of alternative drug therapy options in the treatment of androgenetic alopecia.
J Cosmet Dermatol
October 2024
School of Pharmacy, BRAC University, Dhaka, Bangladesh.
Background: Oral finasteride and topical minoxidil formulations are the only FDA-approved drug therapies for androgenetic alopecia (AGA). Research into dutasteride, topical finasteride, and nontopical minoxidil (low-dose oral and sublingual) formulations in the treatment of AGA has spiked within recent years. Early findings show that these alternative drug therapies may have similar to improved efficacy and safety profiles relative to the conventional treatment options.
View Article and Find Full Text PDFMesotherapy as a Promising Alternative to Minoxidil for Androgenetic Alopecia: A Systematic Review.
Cureus
May 2024
Surgical Oncology, Tata Medical Center, Kolkata, IND.
Patterned hair loss (PHL) is a severe hair condition that affects both sexes. Mesotherapy is a treatment that involves microinjecting medications and/or vitamins into the middle layer of the skin. Mesotherapy reduces systemic adverse effects by delivering drugs directly to the hair follicle, increasing local bioavailability while lowering systemic exposure.
View Article and Find Full Text PDFSystematic review of mesotherapy: a novel avenue for the treatment of hair loss.
J Dermatolog Treat
December 2023
Dermatology Unit, IRCCS Azienda Ospedaliero, Universitaria di Bologna, Italy.
Article Synopsis
- Mesotherapy is a procedure where lower doses of medication are injected into the skin to treat conditions like hair loss, allowing for longer-lasting effects and improved patient compliance.
- A systematic review analyzed 27 studies from a pool of 416 records to assess the effectiveness of mesotherapy for hair loss, focusing on various therapeutic agents used in treatment.
- While some studies indicate significant hair growth improvement from mesotherapy, the lack of standardized treatment protocols and potential side effects highlight the need for more extensive clinical trials.
Pressure alopecias: A review.
J Am Acad Dermatol
January 2024
Trichology Clinic, Department of Dermatology, Hospital General "Dr. Manuel Gea González," Mexico City, Mexico. Electronic address:
Article Synopsis
- Pressure-induced alopecias (PAs) are a rare hair loss condition triggered by restricted blood flow to the scalp due to external pressure, occurring in two types: type 1 from prolonged pressure (such as during surgeries) and type 2 from cosmetic procedures involving injectables.
- Type 2 PA is becoming more common and can be confused with vascular occlusion-induced alopecia, highlighting the need for accurate diagnosis through clinical evaluation and potential use of trichoscopy.
- While hair loss can be evident, the condition is often self-limiting, with most cases seeing hair regrowth; treatment is generally unnecessary, but prognosis varies based on the extent of ischemia and response to timely interventions
Intradermal Delivery of Alopecia Therapeutics: Current State and Future Prospects.
Dermatol Surg
September 2023
Department of Dermatology, The Ronald O. Perelman, NYU Grossman School of Medicine, New York, New York.
Background: Mesotherapy, a technique of transdermal microinjections of specific preparations, is increasingly used in fields such as dermatology and specifically for alopecia treatment. Its popularity stems from its ability to deliver drugs in a targeted manner while minimizing systemic side effects.
Objective: To assess and review current knowledge regarding the use of mesotherapy to deliver alopecia medications and highlight future directions for research.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!