AI Article Synopsis

  • The study examined the impact of previous abdominal surgery (PAS) on the outcomes of colorectal cancer (CRC) surgery by comparing data from 34,827 patients across 14 research studies.
  • Results indicated that patients with PAS experienced higher rates of overall complications (1.12 times more likely), ileus (almost 2 times more likely), and mortality (1.26 times more likely) compared to those without PAS.
  • Despite these findings, short-term outcomes were largely unaffected except for an increase in ileus, suggesting that surgeons should be cautious and proactive in managing PAS patients to minimize risks.

Article Abstract

The current study aimed to investigate whether previous abdominal surgery (PAS) could affect the outcomes of colorectal cancer (CRC) surgery. We conducted the search strategy in three databases (PubMed, Embase, and the Cochrane Library) from inception to May 26, 2022. The short-term and long-term outcomes were compared between the PAS group and the non-PAS group. Odds ratios (ORs) and 95% confidence intervals (CIs) were pooled up. Stata (V.16.0) software was used for data analysis. We included 34,827 patients from 14 studies in the current study. After pooling up all the data, we found that there were higher proportions of overall complications (OR = 1.12, I = 4.65%, 95% CI 1.03 to 1.23, P = 0.01), ileus (OR = 1.96, I = 59.74%, 95% CI 1.12 to 3.44, P = 0.02) and mortality (OR = 1.26, I = 0.00%, 95% CI 1.11 to 1.42, P = 0.00) in the PAS group than the non-PAS group. Patients with a history of PAS had higher risks of overall complications and death following CRC surgery. However, it did not appear to significantly affect the short-term outcomes apart from ileus. Surgeons should raise awareness of patients with a history of PAS, and take steps to reduce postoperative complications and mortality.

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Source
http://dx.doi.org/10.1007/s13304-024-01864-wDOI Listing

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