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General practitioner-centered rural obesity management: Design, protocol and baseline data of the German HAPpEN pragmatic trial.
Prev Med Rep
January 2025
Institute of General Practice, Friedrich-Alexander University Erlangen, Nuernberg, Germany.
Objective: HAPpEN aims to implement and evaluate a holistic general practitioner-centered, interdisciplinary obesity management strategy in rural Germany, focusing on feasibility, health outcomes, and economic benefits.
Methods: HAPpEN is a 12-month, pragmatic single-arm, multicenter trial, informed by a formative survey, and initiated in April 2023 with 98 obese participants (body mass index, BMI ≥ 30 kg/m) in Kulmbach, Germany. The program integrates nutritional counseling, physical activity, and behavior change techniques, including smartphone-based self-monitoring.
Inpatient complications and mortality in cirrhotic patients undergoing bariatric surgery: a comprehensive analysis.
Hosp Pract (1995)
January 2025
Pulmonary and Critical Care Medicine, University of Toledo, Toledo, OH, USA.
Introduction: Liver cirrhosis, a complex and progressive disease,imposes a significant global health burden, characterized by irreversible livertissue scarring and various life-threatening complications. Traditionallylinked to factors like chronic alcohol consumption and viral hepatitisinfections, the rising prevalence of obesity introduces a new dimension to itsetiology. As obesity rates continue to climb worldwide, the confluence of livercirrhosis and bariatric surgery has become an increasingly pertinent andclinically relevant topic of inquiry.
View Article and Find Full Text PDFThe value of growth differentiation factor 15 as a biomarker for peripheral artery disease in diabetes patients.
Diabetol Metab Syndr
January 2025
Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan.
Background: Growth differentiation factor 15 (GDF15) is significantly correlated with glycolipid metabolic disorders. Increased GDF15 levels are associated with obesity, insulin resistance, and diabetes as well as a poorer diabetes progression and prognosis. This is a prospective cohort study investigated the association between circulating GDF15 and diabetic peripheral artery disease.
View Article and Find Full Text PDFComparing myocardial perfusion scan findings in patients with and without Covid-19.
BMC Cardiovasc Disord
January 2025
Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Background: Covid-19 is a pandemic viral disease that directly or indirectly affects multiple organ systems, including the cardiovascular system. SPECT GATED MPI is a non-invasive nuclear imaging modality used to assess myocardial perfusion and function. The aim of this study was to evaluate the effect of Covid-19 pandemic on myocardial perfusion imaging in ischemic heart disease.
View Article and Find Full Text PDFThe association between county-level social determinants of health and cardio-kidney-metabolic disease attributed all-cause mortality in the US: A cross sectional analysis.
Am J Med Sci
January 2025
Case Western Reserve University School of Medicine, Cleveland, USA; Harrington Heart and Vascular Institute, University Hospitals, Cleveland, USA; Louis Stokes Cleveland VA Medical Center, Cleveland, USA. Electronic address:
Background: The American Heart Association recently defined cardio-kidney-metabolic (CKM) syndrome as the intersection between metabolic, renal, and cardiovascular disease. Understanding the contemporary estimates of CKM related mortality in the US is essential for developing targeted public interventions.
Methods: We analyzed state-level and county-level CKM-associated all-cause mortality data (2010-2019) from the CDC Wide-ranging Online Data for Epidemiologic Research (WONDER).
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