AI Article Synopsis
- A study investigated the prevalence of patent foramen ovale (PFO) in Japanese individuals, which had not been well-explored across different ethnic groups.
- The research analyzed 359 hearts from forensic autopsies and found an overall PFO rate of 12.5%, with significantly higher rates in those under 20 years old (66.7% in males and 38.5% in females).
- It was noted that the area of the fossa ovalis (a heart structure) increased with age, and the PFO prevalence in Japanese adults was lower compared to previous studies on White and Black populations.
Article Abstract
Racial and ethnic differences in the prevalence of patent foramen ovale have been suggested, but there are insufficient data to confirm the situation. Studies have also not investigated detailed morphological changes in the fossa ovalis by age. This study therefore aimed to clarify the characteristics of the fossa ovalis and determine the frequency of patent foramen ovale in Japanese people, using materials from forensic autopsies. A total of 359 hearts were obtained during forensic autopsies (from 223 males and 136 females, aged from 0 to 94 years). Overall, prevalence of patent foramen ovale was 12.5%, but it was significantly higher among those under 20 years old (66.7% in males, 38.5% in females). The area of the fossa ovalis linearly increased with age in both sexes. The prevalence of patent foramen ovale was lower in Japanese adults than previously found in either White or Black people. The ratio of the area of the fossa ovalis to the heart weight was nearly constant.
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| http://dx.doi.org/10.2220/biomedres.45.135 | DOI Listing |
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