The good phytotoxicity and selectivity against weeds versus tomato or cress make saponin-rich fractions from , , , and attractive candidates as bioherbicides. The saponin contents have only previously been reported for , and as a consequence, simultaneous dereplication has been performed on saponin-rich fractions from the other plants by mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. This strategy enables the identification of a total of 26 saponins, 14 of which have been described previously and 12 of which are proposed as new saponins. They include isomers and a new sugar chain with a β-d-apiofuranose unit. The method is corroborated by the isolation of eight dereplicated saponins from .
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http://dx.doi.org/10.1021/acs.jafc.4c02308 | DOI Listing |
BMC Complement Med Ther
November 2024
Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt.
Background: Fagonia cretica L. (Family: Zygophyllaceae), is a wild shrub mostly found in Mediterranean districts and extensively used in folk medicine for a vast array of purposes such as antidiabetic and anticancer during the early stages. The goal of the current study was to validate the antioxidant, anti-inflammatory, and cytotoxic properties of Egyptian F.
View Article and Find Full Text PDFPlants (Basel)
September 2024
Allelopathy Group, Department of Organic Chemistry, Institute of Biomolecules (INBIO), School of Science, University of Cádiz, 11510 Puerto Real, Cádiz, Spain.
The genus comprises over 400 species that are known for their diverse applications, which include being sources of fiber, food, and beverages. There has recently been increased interest in exploring the metabolic content of this genus, and in this respect, saponins are the main compounds of interest. Saponins for have not been described to date, and the current work addresses the dereplication of a saponin-rich fraction to identify the structures of six compounds.
View Article and Find Full Text PDFJ Agric Food Chem
June 2024
Allelopathy Group, Department of Organic Chemistry, Institute of Biomolecules (INBIO), Campus de Excelencia Internacional (ceiA3), School of Science, University of Cadiz, C/República Saharaui n° 7, Puerto Real, Cadiz 11510, Spain.
The good phytotoxicity and selectivity against weeds versus tomato or cress make saponin-rich fractions from , , , and attractive candidates as bioherbicides. The saponin contents have only previously been reported for , and as a consequence, simultaneous dereplication has been performed on saponin-rich fractions from the other plants by mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. This strategy enables the identification of a total of 26 saponins, 14 of which have been described previously and 12 of which are proposed as new saponins.
View Article and Find Full Text PDFPhytochem Anal
June 2024
Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Introduction: This research explores sustainable applications for waste generated from fenugreek (Trigonella foenum-graecum), a plant with both nutritional and medicinal uses. The study specifically targets waste components as potential sources of nutrients and bioactive compounds.
Objectives: The focus is to conduct detailed metabolic profiling of fenugreek waste, assess its anti-inflammatory properties by studying its cyclooxygenase (COX) inhibitory effect, and correlate this effect to the metabolite fingerprint.
Nat Prod Res
June 2024
Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India.
The aim of the present study was to evaluate the role of in acetic-acid-induced ulcerative colitis in mice. Acetic acid (3%v/v, in 0.9% saline) was infused intrarectally to induce ulceration in mice.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!